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Y0001099

Valaciclovir impurity G

European Pharmacopoeia (EP) Reference Standard

Synonim(y):

4-(Dimethylamino)pyridine, N,N-Dimethylpyridin-4-amine, DMAP

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About This Item

Wzór empiryczny (zapis Hilla):
C7H10N2
Numer CAS:
1122-58-3
Masa cząsteczkowa:
122.17
Beilstein:
110354
Numer MDL:
MFCD00006418
Kod UNSPSC:
41116107
Identyfikator substancji w PubChem:
329831263
NACRES:
NA.24

klasa czystości

pharmaceutical primary standard

rodzina API

valacyclovir

producent / nazwa handlowa

EDQM

mp

108-110 °C (lit.)

Zastosowanie

pharmaceutical (small molecule)

format

neat

temp. przechowywania

2-8°C

ciąg SMILES

CN(C)c1ccncc1

InChI

1S/C7H10N2/c1-9(2)7-3-5-8-6-4-7/h3-6H,1-2H3

Klucz InChI

VHYFNPMBLIVWCW-UHFFFAOYSA-N

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Opis ogólny

4-(Dimethylamino)pyridine (DMAP) is an excellent catalyst for acylation of hindered alcohols and in chemical transformations. It is highly nucleophilic in nature.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Zastosowanie

A highly efficient catalyst for acylation reactions

Opakowanie

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Inne uwagi

Sales restrictions may apply.

Hasło ostrzegawcze

Danger

Zwroty wskazujące rodzaj zagrożenia

H301 + H331,H310,H315,H318,H370,H411

Klasyfikacja zagrożeń

Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 1

Organy docelowe

Nervous system

Kod klasy składowania

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

255.2 °F

Temperatura zapłonu (°C)

124 °C

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Certyfikaty analizy (CoA)

Lot/Batch Number

Sorry, we don't have COAs for this product available online at this time.

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Configurationally Stable Biaryl Analogues of 4-(Dimethylamino) pyridine: A Novel Class of Chiral Nucleophilic Catalysts.
Spivey, Alan C., et al.
The Journal of Organic Chemistry, 64.26, 9430-9443 (1999)
Bryan Hoang et al.
International journal of pharmaceutics, 471(1-2), 224-233 (2014-05-24)
Docetaxel (DTX) remains the only effective drug for prolonging survival and improving quality of life of metastatic castration resistant prostate cancer (mCRPC) patients. Despite some clinical successes with DTX-based therapies, advent of cumulative toxicity and development of drug resistance limit
Aniruddha Roy et al.
Molecular pharmaceutics, 11(8), 2592-2599 (2014-02-26)
Taxanes are a class of anticancer agents with a broad spectrum and have been widely used to treat a variety of cancer. However, its long-term use has been hampered by accumulating toxicity and development of drug resistance. The most extensively
Masahiro Murakami et al.
Acta biomaterialia, 10(11), 4723-4729 (2014-07-20)
The objective of this study is to design a drug delivery system (DDS) for the in vivo promotion of macrophage recruitment. As the drug, a water-insoluble agonist of sphingosine-1-phosphate type 1 receptor (SEW2871) was selected. SEW2871 (SEW) was water-solubilized by
Junya Ito et al.
Journal of chromatography. A, 1386, 53-61 (2015-02-18)
Increasing evidence suggests that phospholipid peroxidation plays important roles in the pathogenesis of various diseases, such as atherosclerosis. With regard to the biochemical processes that initiate phospholipid peroxidation in vivo, enzymatic conversion of phosphatidylcholine to phosphatidylcholine hydroperoxide (PCOOH) by lipoxygenase
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