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46482

Naproxen

Name: Naproxen
Brand: SIAL
Price: 473 PLN

VETRANAL^®, analytical standard

Synonim(y):

(S)-(+)-6-Methoxy-α-methyl-2-naphthaleneacetic acid, (S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid

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Gabaryty przesyłki	SKU	Dostępność	Cena netto
250 mg		Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności	473,00 zł

Informacje o tej pozycji

Wzór liniowy:

CH₃OC₁₀H₆CH(CH₃)CO₂H

Numer CAS:

22204-53-1

Masa cząsteczkowa:

230.26

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329757200

EC Number:

244-838-7

Beilstein/REAXYS Number:

3591068

MDL number:

MFCD00010500

473,00 zł

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Pomoc techniczna

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Pozwól nam pomóc

grade

analytical standard

Quality Level

200

agency

EPA 1694

product line

VETRANAL^®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

152-154 °C (lit.)

application(s)

clinical
environmental
forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

COc1ccc2cc(ccc2c1)[C@H](C)C(O)=O

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Analytical Chromatography

Chromatography Standards

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Ta pozycja	N6142	PHR1165	PHR1040
Supelco 46482 Naproxen	Supelco N6142 Nabumetone	Supelco PHR1165 Naproxen sodium	Supelco PHR1040 Naproxen
technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) HPLC: suitable, gas chromatography (GC): suitable
format neat	format neat	format neat	format neat
application(s) clinical environmental forensics and toxicology pharmaceutical (small molecule)	application(s) forensics and toxicology pharmaceutical (small molecule) veterinary	application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)
grade analytical standard	grade analytical standard	grade certified reference material, pharmaceutical secondary standard	grade certified reference material, pharmaceutical secondary standard
agency EPA 1694	agency -	agency traceable to USP 1457403	agency traceable to BP 435, traceable to Ph. Eur. N0250000, traceable to USP 1457301
product line VETRANAL^®	product line -	product line -	product line -

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Non-selective cyclooxygenase (COX-1 and COX-2) inhibitor.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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pictograms

GHS08,GHS07,GHS09

signalword

Warning

hcodes

H302,H315,H319,H335,H361fd,H411

pcodes

P202 - P273 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Klasa składowania

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certyfikaty analizy (CoA)

Lot/Batch Number

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Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Separation of (R)- and (S)-naproxen using micellar chromatography and an alpha 1-acid-glycoprotein column: application for chiral monitoring in human liver microsomes by coupled-column chromatography.

D Haupt et al.

Journal of biochemical and biophysical methods, 25(4), 273-284 (1992-12-01)

A column-switching system for fast determination of (R)- and (S)-naproxen in liver microsomes has been developed. The centrifuged sample was injected directly onto a pre-column with octadecylcoated silica. The retained analytes were then directed to an alpha 1-AGP column using

A hydrogen sulfide-releasing cyclooxygenase inhibitor markedly accelerates recovery from experimental spinal cord injury.

Michela Campolo et al.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 27(11), 4489-4499 (2013-08-01)

Spinal cord trauma causes loss of motor function that is in part due to the ensuing inflammatory response. Hydrogen sulfide (H2S) is a potent, endogenous anti-inflammatory and neuroprotective substance that has been explored for use in the design of novel

Renal effects of selective cyclooxygenase-2 inhibition in normotensive salt-depleted subjects.

J Rossat et al.

Clinical pharmacology and therapeutics, 66(1), 76-84 (1999-08-03)

To compare the renal hemodynamic and tubular effects of celecoxib, a selective inhibitor of cyclooxygenase-2 (COX-2) to those of naproxen, a nonselective inhibitor of cyclooxygenases in salt-depleted subjects. Forty subjects were randomized into four parallel groups to receive 200 mg

Carbamazepine and naproxen: fate in wetland mesocosms planted with Scirpus validus.

Dong Qing Zhang et al.

Chemosphere, 91(1), 14-21 (2012-12-27)

Scirpus validus was grown hydroponically and exposed to the pharmaceuticals, carbamazepine and naproxen at concentrations of 0.5-2.0 mg L(-1) for an exposure duration of up to 21 d. By the end of experiment, carbamazepine elimination from the nutrient solution reached

D-amino acids boost the selectivity and confer supramolecular hydrogels of a nonsteroidal anti-inflammatory drug (NSAID).

Jiayang Li et al.

Journal of the American Chemical Society, 135(2), 542-545 (2012-11-10)

As systemically used therapeutics for treating acute or chronic pains or inflammations, nonsteroidal anti-inflammatory drugs (NSAIDs) also associate with the adverse gastrointestinal and renal effects and cardiovascular risks. Thus, it is beneficial to develop topical gels that selectively inhibit cyclooxygenase-2

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Numer pozycji handlu globalnego

SKU	NUMER GTIN
46482-250MG	04061832356648

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