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Sigma-Aldrich

Cysteamine hydrochloride

≥97.0% (RT)

Synonim(y):

β-Mercapto­ethylamine hydrochloride, 2-Amino­ethane­thiol hydrochloride, 2-Mercapto­ethyl­amine hydrochloride, Decarboxy­cysteine hydrochloride, Thio­ethanol­amine hydrochloride

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About This Item

Wzór liniowy:
HSCH2CH2NH2 · HCl
Numer CAS:
156-57-0
Masa cząsteczkowa:
113.61
Beilstein:
3590083
Numer WE:
205-858-1
Numer MDL:
MFCD00012904
Kod UNSPSC:
41106305
Identyfikator substancji w PubChem:
329753425
NACRES:
NA.51

Poziom jakości

200

Próba

≥97.0% (RT)

Postać

crystals

mp

64-70 °C
67-71 °C

temp. przechowywania

2-8°C

ciąg SMILES

Cl[H].NCCS

InChI

1S/C2H7NS.ClH/c3-1-2-4;/h4H,1-3H2;1H

Klucz InChI

OGMADIBCHLQMIP-UHFFFAOYSA-N

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Zastosowanie

Cysteamine hydrochloride has been used in the in-situ generation of chiral cysteamine-capped cadmium sulfide quantum dots (CA-CdS QDs) for the sensing of Cd2+ and S2-.

Działania biochem./fizjol.

Cysteamine hydrochloride is derived from the degradation of coenzyme A endogenously. Its concentration in plasma is low. It is commonly used as a drug for the orphan disease cystinosis, a lysosomal storage disorder, in which cysteamine decreases intralysosomal cystine accumulation.
Cysteamine is an aminothiol that can reduce important oxidized disulfide molecules such as cystine to yield cysteine. Cysteamine is used in a wide range of applications from regulation of gene expression, to depletion of somatostatin, to coating of nanoparticles.
This page may contain text that has been machine translated.

Piktogramy

Exclamation mark
GHS07

Hasło ostrzegawcze

Warning

Zwroty wskazujące rodzaj zagrożenia

H302,H317,H319,H335

Klasyfikacja zagrożeń

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Sens. 1 - STOT SE 3

Organy docelowe

Respiratory system

Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

dust mask type N95 (US), Eyeshields, Gloves

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Certyfikaty analizy (CoA)

Lot/Batch Number
BCCL6109
BCCM1451
BCCK2275
BCCH7252
BCCG0901

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

A circular dichroism sensor for selective detection of Cd2+ and S2- based on the in-situ generation of chiral CdS quantum dots
Sianglam P, et al.
Spectrochemical Analysis by Atomic Absorption and Emission, 183, 408-416 (2017)
Mengxiao Yu et al.
Journal of the American Chemical Society, 133(29), 11014-11017 (2011-07-01)
pH regulates many cellular processes and is also an indicator of disease progression. Therefore, pH-responsive materials often serve as either tools in the fundamental understanding of cell biology or medicine for disease diagnosis and therapy. While gold nanoparticles have broad
Nida Zaman Khan et al.
ACS omega, 6(40), 25926-25939 (2021-10-19)
Heparin-induced thrombocytopenia (HIT) antibodies (Abs) can mediate and activate blood cells, forming blood clots. To detect HIT Abs, immunological assays with high sensitivity (≥95%) and fast response are widely used, but only about 50% of these tests are accurate as
Martine Besouw et al.
Drug discovery today, 18(15-16), 785-792 (2013-02-19)
Cysteamine is an amino thiol with the chemical formula HSCH2CH2NH2. Endogenously, cysteamine is derived from coenzyme A degradation, although its plasma concentrations are low. Most experience with cysteamine as a drug originates from the field of the orphan disease cystinosis
Rajib Ghosh et al.
Biomaterials, 34(3), 807-816 (2012-11-01)
Lack of affordable technologies for delivering microRNAs and siRNAs into cells on a large scale has hindered our efforts to rapidly parse through hundreds of dysregulated genes/microRNAs in order to identify drivers of complex diseases. The instability and polyanionic nature
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