00200595

Quercetin dihydrate

primary reference standard

• Synonim(y): 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one dihydrate, 3,3′,4′,5,7-Pentahydroxyflavone dihydrate
• Wzór empiryczny (zapis Hilla): C₁₅H₁₀O₇ · 2H₂O
• Numer CAS: 6151-25-3
• Masa cząsteczkowa: 338.27
• EC Number: 204-187-1
• UNSPSC Code: 85151701
• NACRES: NA.24
• Colour Index Number: 75670
• Beilstein/REAXYS Number: 317313

Właściwości

• grade: primary reference standard
• form: powder
• shelf life: limited shelf life, expiry date on the label
• manufacturer/tradename: HWI
• technique(s): HPLC: suitable, chromatography: suitable, gas chromatography (GC): suitable
• mp: >300 °C (lit.)
• SMILES string: OC(C(O)=C1)=CC=C1C2=C(O)C(C3=C(O)C=C(O)C=C3O2)=O
• InChI: 1S/C15H10O7.2H2O/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6;;/h1-5,16-19,21H;2*1H2
• InChI key: GMGIWEZSKCNYSW-UHFFFAOYSA-N

Opis

General description

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Application

Reference standard in the analysis of herbal medicinal products.

Biochem/physiol Actions

Quercetin dihydrate is a flavonoid with anticancer activity.

Quercetin dihydrate is a flavonoid with anticancer activity. Quercetin is a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Quercetin has antiproliferative effects on cancer cell lines, reduces cancer cell growth via type II estrogen receptors, and arrests human leukemic T cells in late G1 phase of the cell cycle.

Other Notes

This compound is commonly found in plants of the genus: allium angelica arnica carum echinacea eucalyptus ginkgo glycyrrhiza lycium pimpinella primula sambucus silybum

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS06
• Słowo ostrzegawcze: Danger
• Klasa składowania: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Co się dzieje?: WGK 1
• Kody zagrożeń: H301,H315,H319
• Ostrzeżenia: P264 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338 - P332 + P313
• Hazard Classifications: Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2