P3B030D10

Pellicon^® 3 Cassette with Biomax^® Membrane

30 kDa, D screen, 1.14 m²

• Synonim(y): Pellicon^® 3 Cassette with Biomax 30 kDa Membrane, D screen, 1.14 m²
• Kod UNSPSC: 23151806
• eCl@ss: 32031623

Właściwości

• Materiały: TPE seal; polyethersulfone membrane; polypropylene housing; polypropylene screen; stainless steel cap (for end; polypropylene-encapsulated)
• Poziom jakości: 400
• producent / nazwa handlowa: Pellicon^®
• warunki przechowywania: do not freeze
• Parametry: 30 psi max. reverse press. exposure at 25 °C (for 24 hours); 4-6 L/min-m² recirculation rate; 4-8 L/min-m² flow rate; 40 psi max. transmembrane pressure at 4-50 °C; 6.9 bar max. inlet pressure (100 psi); 80 psi max. transmembrane pressure at 4-40 °C
• metody: tangential flow filtration (TFF): suitable; ultrafiltration: suitable
• Wysokość: 4.2 cm (1.67 in.)
• Długość: 20.6 cm (8.1 in.)
• Szerokość: 17.8 cm (7 in.)
• powierzchnia filtracyjna: 1.14 m²
• rozmiar: 229 mL , Volume (feed); 88 mL , Volume (permeate)
• substancje ekstrahujące się grawimetrycznie: ≤1500 mg/m²
• Matryca: Biomax^®
• wielkość porów: (30 kDa)
• pH: 1-14
• temp. przechowywania: 2-8°C

Opis

Opis ogólny

Pellicon^® 3 cassettes with Biomax membrane are the optimum tangential flow filtration (TFF) devices for the filtration of solutions containing therapeutical proteins, albumin, hormones, vaccines and growth factors. These advanced, high-performance cassettes are ideal for today’s higher titer therapeutic antibodies, higher viscosity feed formulations as well as the more demanding filtration processes that require higher operating pressures, temperatures and caustic cleaning regimes.From small-scale to full-scale production, Pellicon^® 3 cassettes are designed for use in research, process scale-up/scale-down, applications development and full-scale manufacturing. The Pellicon^® 3 design and automated manufacturing process provides unbeatable performance consistency between cassette sizes. Pellicon^® 3 devices also offer greater cassette size selection for improved scale-up and scale-down process development. The streamlined design allows operators to quickly and easily handle, install and remove Pellicon^® 3 cassettes. The materials of construction are compatible with a broad range of chemical cleaning.

Zastosowanie

monoclonal antibodies, recombinant and non-recombinant proteins, vaccines

Cechy i korzyści

• Robust, void-free membrane provides optimum productretention and performance consistency
• Unique feed screen design enables high mass transfer, flux for higher finalconcentration
• Fast, reliable scale up/down from lab to production scale
• Automated manufacturing delivers unbeatable performance consistency andreliability
• Easy to install and clean
• Extreme temperature and chemical compatibility

Inne uwagi

These products are manufactured in a facility which adheres to Good Manufacturing Practices.

Komentarz do analizy

Gravimetric Extractables: after 24 hours in water at controlled room temperature

Informacje prawne

BIOMAX is a registered trademark of Merck KGaA, Darmstadt, Germany

Pellicon is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 10 - Combustible liquids
• Klasa zagrożenia wodnego (WGK): WGK 1