MABT63

Anti-Nectin-3/PVRL3 (CD113) Antibody, clone N3.12.4

clone N3.12.4, from mouse

• Synonim(y): poliovirus receptor-related 3, poliovirus receptor-related protein 3, nectin 3, nectin-3, Nectin-3, CD113 antigen
• Kod UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: mouse
• Poziom jakości: 100
• forma przeciwciała: purified immunoglobulin
• rodzaj przeciwciała: primary antibodies
• klon: N3.12.4, monoclonal
• reaktywność gatunkowa: human
• metody: flow cytometry: suitable
• izotyp: IgG2aκ
• numer dostępu NCBI: NP_056295
• numer dostępu UniProt: Q9NQS3
• Warunki transportu: wet ice
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... NECTIN3(25945)

Opis

Opis ogólny

Nectin-3, also known as Poliovirus receptor-related protein 3 (PVRL3) and PRR3, is thought to work with cadherin to form cell-cell adherens junctions. It is a transmembrane protein that is commonly found in the testis and in placental tissue. Nectin-3 colocalizes with CD155, the cognate receptor for poliovirus, to cell-cell junctions. Nectin-3′s involvement in down-regulation PVR from the cell surface leads to a reduction in cell motility and proliferation.

Immunogen

Full length recombinant protein corresponding to human Nectin-3.

Zastosowanie

Anti-Nectin-3/PVRL3 (CD113) Antibody, clone N3.12.4 detects level of Nectin-3/PVRL3 (CD113) & has been published & validated for use in FC.

Research Category
Cell Structure

Research Sub Category
ECM Proteins

Jakość

Evaluated by Flow Cytometry in U251 cells.

Flow Cytometry Analysis: 0.1 µg of this antibody detected Nectin-3 in U251 cells.

Opis wartości docelowych

61 kDa calculated

Postać fizyczna

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Przechowywanie i stabilność

Stable for 1 year at 2-8°C from date of receipt.

Komentarz do analizy

Control
U251 cells

Inne uwagi

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable