MABC580
Przeciwciało przeciw łańcuchowi ciężkiemu klatryny, klon 6F10.1
clone 6F10.1, from mouse
Synonim(y):
Clathrin heavy chain 1, Clathrin Heavy Chain, Clathrin heavy chain on chromosome 17, CLH-17
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Informacje o tej pozycji
biological source
mouse
Quality Segment
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
6F10.1, monoclonal
species reactivity
human, mouse, rat
technique(s)
flow cytometry: suitable, immunocytochemistry: suitable, western blot: suitable
isotype
IgG2aκ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... CLTC(1213)
General description
Immunogen
Application
Analiza immunocytochemiczna: 25,0 µg/ml z reprezentatywnej partii wykryło łańcuch ciężki klatryny w komórkach HeLa, A431, HUVEC i NIH/3T3.
Physical form
Analysis Note
Western Blotting Analysis: 0.5 µg/mL of this antibody detected Clathrin Heavy Chain in 10 µg of PC12 cell lysate.
Other Notes
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Klasa składowania
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certyfikaty analizy (CoA)
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Powiązane treści
A major focus of breast cancer research is to understand the mechanisms responsible for disease progression and drug resistance. Toward that end, it has been found that approximately two thirds of all human breast carcinomas overexpress the Estrogen Receptor α (ERα) protein and it remains the primary pharmacological target for endocrine therapy1,2. The normal cellular function of ERα is as a transcription factor that mediates a wide variety of physiological processes, many of which are dependent upon phosphorylation of the receptor at specific amino acid residues3,4. Indeed, ERα is known to be phosphorylated at a multitude of different sites, yet how these all correlate to disease remains unclear5. Here, we interrogated multiple sites of ERα for phosphorylation status by screening an extensive panel of different breast cancer patient samples and other non-breast cancer tissue microarray (TMA) slide samples to determine their relevance to disease.
Numer pozycji handlu globalnego
| SKU | NUMER GTIN |
|---|---|
| MABC580 | 04055977166620 |