ABN483

Anti-RTP801 Antibody

from rabbit, purified by affinity chromatography

• Synonim(y): DNA damage-inducible transcript 4 protein, HIF-1 responsive protein RTP801, Protein regulated in development and DNA damage response 1, REDD-1, RTP801
• Kod UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: rabbit
• forma przeciwciała: affinity isolated antibody
• rodzaj przeciwciała: primary antibodies
• klon: polyclonal
• oczyszczone przez: affinity chromatography
• reaktywność gatunkowa: mouse, human
• metody: immunohistochemistry: suitable; western blot: suitable
• numer dostępu UniProt: Q9NX09
• Warunki transportu: wet ice
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... DDIT4(54541)

Opis

Opis ogólny

HIF-1 responsive protein RTP801, also known as DNA damage-inducible transcript 4 protein, is a member of the DDIT4 family regulating cell growth, proliferation and survival via inhibition of the activity of the mammalian target of rapamycin complex 1 (mTORC1). In response to energy stress, RTP801 inhibits mTOR function, resulting in dephosphorylation of downstream targets such as ribosomal protein S6 kinase 1 and 4EBP1 and decreasing cell growth. RTP801 is widely expressed with lowest levels in brain, skeletal muscle, and intestine.

Immunogen

KLH-conjugated linear peptide corresponding to human RTP801.

Zastosowanie

Detect HIF-1 responsive protein RTP801 using this rabbit polyclonal antibody, Anti-RTP801 Antibody validated for use in western blotting & IHC.

Immunohistochemistry Analysis: 5 µg/mL from a representative lot detected RTP801 in mouse kidney tissue.

Research Category
Neuroscience

Research Sub Category
Developmental Neuroscience

Jakość

Evaluated by Western Blotting in human kidney tissue lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected RTP801 in 15 µg of human kidney tissue lysate.

Opis wartości docelowych

~25 kDa observed. Uncharacterized bands may appear in some lysates.

Postać fizyczna

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Przechowywanie i stabilność

Stable for 1 year at 2-8°C from date of receipt.

Komentarz do analizy

Control
Human kidney tissue lysate

Inne uwagi

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 10 - Combustible liquids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable