ABC832

Anti-TMEM16B Antibody

from rabbit, purified by affinity chromatography

• Synonim(y): Anoctamin-2, Transmembrane protein 16B
• Kod UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: rabbit
• Poziom jakości: 100
• forma przeciwciała: affinity isolated antibody
• rodzaj przeciwciała: primary antibodies
• klon: polyclonal
• oczyszczone przez: affinity chromatography
• reaktywność gatunkowa: human, rat
• metody: immunofluorescence: suitable; immunohistochemistry: suitable; western blot: suitable
• numer dostępu UniProt: Q9NQ90
• Warunki transportu: wet ice
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... ANO2(57101)

Opis

Opis ogólny

Anoctamin-2, also known as Transmembrane protein 16B (TMEM16B) are subunits of Calcium-activated chloride channels (CaCC) which mediate physiological functions such as epithelial secretion, sensory signal transduction, and smooth muscle contraction. TMEM16B is predicted to have eight transmembrane domains with both the amino and carboxy termini in the cytoplasm and is expressed in several tissues including olfactory sensory neurons as well as photoreceptors in mammalian retina. Like TMEM16A, TMEM16B is thought to form at least part of CaCC’s but has different biophysical characteristics such as voltage dependence and unitary conductance.

Specyficzność

This antibody will not cross-react with TMEM16A.

Immunogen

Epitope: N-terminus

KLH-conjugated synthetic peptide corresponding to the N-terminus of human TMEM16B.

Zastosowanie

Anti-TMEM16B Antibody is an antibody against TMEM16B for use in western blotting, IHC & immunofluorescence.

Immunohistochemistry Analysis: 5 μg/mL from a representative lot detected TMEM16B in human brain tissue.

Immunofluorescence Analysis: 20 μg/mL from a representative lot detected TMEM16B in human brain cells.

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

Jakość

Evaluated by Western Blotting in rat brain tissue.

Western Blotting Analysis: 2 μg/mL of this antibody detected TMEM16B in rat brain tissue.

Opis wartości docelowych

~128 kDa observed. Uncharacterized bands may be observed in some lysate(s).

Postać fizyczna

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Przechowywanie i stabilność

Stable for 1 year at 2-8°C from date of receipt.

Inne uwagi

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 10 - Combustible liquids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable