475880
ML-7 Hydrochloride
>98% (TLC), protein kinase A and C inhibitor, solid
Synonim(y):
ML-7, Hydrochloride, 1-(5-Iodonaphthalene-1-sulfonyl)homopiperazine, HCl
Wybierz wielkość
| Rozmiar/SKU | Dostępność | Cena netto |
|---|---|---|
1 mg | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 819,00 zł |
Informacje o tej pozycji
819,00 zł
Nazwa produktu
ML-7, Hydrochloride, A cell-permeable, potent, reversible, ATP-competitive, and selective inhibitor of myosin light chain kinase (Ki = 300 nM).
Quality Segment
assay
>98% (TLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated (hygroscopic), protect from light
color
white
solubility
50% ethanol: 4.5 mg/mL, DMSO: 4.5 mg/mL
shipped in
ambient
storage temp.
2-8°C
SMILES string
Ic1c2c(c(ccc2)[S](=O)(=O)N3CCNCCC3)ccc1
InChI
1S/C15H17IN2O2S/c16-14-6-1-5-13-12(14)4-2-7-15(13)21(19,20)18-10-3-8-17-9-11-18/h1-2,4-7,17H,3,8-11H2
InChI key
GEHJIACZUFWBTK-UHFFFAOYSA-N
General description
Biochem/physiol Actions
Myosin light chain kinase (Mlck)
Preparation Note
Other Notes
Saitoh, M., et al. 1987. J. Biol. Chem.262, 7796.
Legal Information
Disclaimer
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Ta pozycja | |||
|---|---|---|---|
| description A cell-permeable, potent, reversible, ATP-competitive, and selective inhibitor of myosin light chain kinase (Ki = 300 nM). | description A cell-permeable and reversible calmodulin antagonist that inhibits myosin light chain kinase (IC50 = 51 µM) and Ca2+-calmodulin-dependent phosphodiesterase (IC50 = 28 µM). | description An enhanced water-soluble form of Bisindolylmaleimide I. | description A cell-permeable and reversible calmodulin antagonist that inhibits myosin light chain kinase (IC50 = 230 µM) and Ca2+-calmodulin-dependent phosphodiesterase (IC50 = 240 µM). |
| form solid | form crystalline solid | form solid | form crystalline solid |
| assay >98% (TLC) | assay ≥98% (TLC) | assay ≥95% (HPLC) | assay ≥98% (NMR) |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| manufacturer/tradename Calbiochem® | manufacturer/tradename Calbiochem® | manufacturer/tradename Calbiochem® | manufacturer/tradename Calbiochem® |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| storage condition protect from light, OK to freeze, desiccated (hygroscopic) | storage condition desiccated (hygroscopic), protect from light, OK to freeze | storage condition OK to freeze | storage condition OK to freeze, desiccated (hygroscopic), protect from light |
Klasa składowania
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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