218755

Caspase-4 Inhibitor I

The Caspase-4 Inhibitor I, also referenced under CAS 402832-01-3, controls the biological activity of Caspase-4. This small molecule/inhibitor is primarily used for Cancer applications.

• Synonim(y): Caspase-4 Inhibitor I, Ac-LEVD-CHO
• Wzór empiryczny (zapis Hilla): C₂₂H₃₆N₄O₉
• Numer CAS: 402832-01-3
• Masa cząsteczkowa: 500.54
• MDL number: MFCD08703162
• UNSPSC Code: 12352200
• NACRES: NA.54
• Assay: ≥95% (HPLC)
• Form: lyophilized solid
• Storage condition: OK to freeze

Właściwości

• Quality Segment: 100
• assay: ≥95% (HPLC)
• form: lyophilized solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: white
• solubility: water: 1 mg/mL
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: N([C@@H](C(C)C)C(=O)N[C@@H](CC(=O)O)C=O)C(=O)[C@@H](NC(=O)[C@@H](NC(=O)C)CC(C)C)CCC(=O)O
• InChI: 1S/C22H36N4O9/c1-11(2)8-16(23-13(5)28)21(34)25-15(6-7-17(29)30)20(33)26-19(12(3)4)22(35)24-14(10-27)9-18(31)32/h10-12,14-16,19H,6-9H2,1-5H3,(H,23,28)(H,24,35)(H,25,34)(H,26,33)(H,29,30)(H,31,32)/t14-,15-,16-,19-/m0/s1
• InChI key: MXGJLIBJKIIQSF-FPXQBCRKSA-N

Opis

General description

A reversible caspase-4 (ICH-2) inhibitor.

A reversible caspase-4 inhibitor.

Biochem/physiol Actions

Cell permeable: no

Primary Target
caspase-4

Product does not compete with ATP.

Reversible: yes

Preparation Note

Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Ac-Leu-Glu-Val-Asp-CHO

Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Talanian, R.V., et al. 1997. J. Biol. Chem. 272, 9677.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable