197225

Bcl-2 Binding Peptide, Cell-Permeable, Negative Control

A cell-permeable, mutated cpm-1285 peptide analog (Leu¹⁵¹ replaced by Ala) that does not induce apoptosis and displays nearly 15-fold reduction in Bcl-2 binding.

• Synonim(y): Bcl-2 Binding Peptide, Cell-Permeable, Negative Control, Decanoyl-KN¹⁴⁰LWAAQRYGREARRMSDEFEGSFKGL¹⁶⁵-OH, cpm-1285m, cpm-1285m, Decanoyl-KN¹⁴⁰LWAAQRYGREARRMSDEFEGSFKGL¹⁶⁵-OH
• Wzór empiryczny (zapis Hilla): C₁₅₀H₂₃₄N₄₄O₄₂S
• Masa cząsteczkowa: 3357.80
• Kod UNSPSC: 12352200
• NACRES: NA.77

Właściwości

• Poziom jakości: 100
• Próba: ≥95% (HPLC)
• Postać: solid
• producent / nazwa handlowa: Calbiochem^®
• warunki przechowywania: OK to freeze; desiccated (hygroscopic)
• kolor: off-white
• rozpuszczalność: DMSO: 10 mg/mL
• Warunki transportu: ambient
• temp. przechowywania: −20°C

Opis

Opis ogólny

A cell-permeable, mutated cpm-1285 peptide analog (Leu¹⁵¹ replaced by Ala) that does not induce apoptosis and displays nearly 15-fold reduction in Bcl-2 binding. Suitable for use as a negative control for Cat. No. 197220.

A cell-permeable, mutated cpm-1285 peptide analog where Leu¹⁵¹ is replaced by Ala. Does not induce apoptosis and displays about 15 fold lower Bcl-2 binding. Suitable for use as a negative control.

Działania biochem./fizjol.

Cell permeable: yes

Primary Target
A negative control for Cat. No. 197220 (Bcl-2 Binding Peptide, Cell-Permeable).

Product does not compete with ATP.

Reversible: no

Opakowanie

Packaged under inert gas

Ostrzeżenie

Toxicity: Standard Handling (A)

Sekwencja

CH₃(CH₂)₈CONH-Lys-Asn-Leu-Trp-Ala-Ala-Gln-Arg-Tyr-Gly-Arg-Glu-Ala-Arg-Arg-Met-Ser-Asp-Glu-Phe-Glu-Gly-Ser-Phe-Lys-Gly-Leu-OH

Postać fizyczna

Supplied as a trifluoroacetate salt.

Rekonstytucja

Following reconstitution, aliquot, flush with an inert gas, and freeze at -20°C. Stock solutions are stable for up to 2 weeks at -20°C.

Inne uwagi

Wang, J-L., et al. 2000. Cancer Res.60, 1498.

Informacje prawne

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable