189482

Peptyd hamujący związany z autokamtydem-2, mirystoilowany

≥97% (HPLC), CaM kinase II inhibitor, lyophilized

• Synonim(y): Myrystoilowany AIP, Myr-N-KKALRRQGAVDAL-OH
• Wzór empiryczny (zapis Hilla): C₇₈H₁₄₂N₂₂O₂₀
• Masa cząsteczkowa: 1708.10
• UNSPSC Code: 12352202
• NACRES: NA.77
• Assay: ≥97% (HPLC)
• Form: lyophilized
• Storage condition: OK to freeze, desiccated (hygroscopic)

Właściwości

• Nazwa produktu: Peptyd hamujący związany z autokamtydem-2, mirystoilowany, The Autocamtide-2 Related Inhibitory Peptide, Myristoylated controls the biological activity of calmodulin-dependent protein kinase II. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
• Quality Segment: 100
• assay: ≥97% (HPLC)
• form: lyophilized
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze, desiccated (hygroscopic)
• solubility: water: 1 mg/mL
• shipped in: ambient
• storage temp.: −20°C

Opis

General description

This peptide corresponds to AIP (Cat. No. 189480 ) which has been myristoylated at the N-terminus, thus enhancing its cell-permeability.

Biochem/physiol Actions

Reversible: no

Target IC₅₀: 40 nM against cam Kinase-2

Cell permeable: yes

Primary Target
Calmodulin-Dependent Protein Kinase (CaM Kinase)-2

Product does not compete with ATP.

Physical form

Supplied as a trifluoroacetate salt.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Gailly, P., et al. 1998. Cell Calcium 24, 293.
Ishida, A., and Fujisawa, H. 1995. J. Biol. Chem.270, 2163.
Ishida, A., et al. 1995. Biochem. Biophys. Res. Commun.212, 806.

Myr-N-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu-OH

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable