05-168

Anti-TNFα Antibody, clone MPG-XT3

clone MPG-XT3, Upstate^®, from rat

• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Conjugate: unconjugated
• Clone: MPG-XT3, monoclonal
• Application: Neutral
• Citations: 11

Properties

• biological source: rat
• Quality Segment: 100
• conjugate: unconjugated
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: MPG-XT3, monoclonal
• species reactivity: mouse
• manufacturer/tradename: Upstate^®
• technique(s): neutralization: suitable
• isotype: IgG1
• NCBI accession no.: NM_000594.2
• UniProt accession no.: P01375
• shipped in: dry ice
• target post-translational modification: unmodified
• Gene Information: human ... TNF(7124)

Description

General description

17 kDa

The concentration of antibody needed to neutralize the bioactivity of TNF-α will depend on the cell type, the incubation conditions, and the biological response studied.

Immunogen

Recombinant murine TNF-α

Application

Research Category
Signaling

Research Sub Category
Growth Factors & Receptors

This Anti-TNFalpha Antibody, clone MPG-XT3 is validated for use in NEUT for the detection of TNFα.

Biochem/physiol Actions

mouse TNF-α; does not recognize human or rat TNF-α

Physical form

0.01M Tris-glycine, 0.15M NaCl, pH 7.4

DEAE chromatography

Format: Purified

Preparation Note

2 years at -20°C

Analysis Note

routinely used to neutralize 50% of the cytotoxic effect of recombinant mouse TNF-α on actinomycin D treated L929 cells.

Other Notes

Replaces: 04-1114

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable