860461P

N-C12-desoxymethylsphinganine

N-lauroyl-1-desoxymethylsphinganine (m17:0/12:0), powder

• Synonim(y): N-dodecanoyl-1-desoxymethylsphinganine (m17:0/12:0); N-C12-1-desoxyMeDHCer; 110959
• Wzór empiryczny (zapis Hilla): C₂₉H₅₉NO₂
• Numer CAS: 1246298-41-8
• Masa cząsteczkowa: 453.78
• Numer MDL: MFCD00066101
• Kod UNSPSC: 12352211
• NACRES: NA.25

Właściwości

• Próba: >99% (TLC)
• Formularz: powder
• opakowanie: pkg of 1 × 1 mg (860461P-1mg)
• producent / nazwa handlowa: Avanti Research^™ - A Croda Brand 860461P
• typ lipidu: sphingolipids; bioactive lipids
• Warunki transportu: dry ice
• temp. przechowywania: −20°C

Opis

Opis ogólny

Commonly referred to as 1-desoxymethyldihydroceramide (1-desoxyMeDHCer), this product is the N-acylated form of 1-desoxymethylsphinganine, a potent inhibitor of sphingolipid metabolism. The biological activity of 1-desoxyMeDHCer is not clearly understood at this time.

N-C12-desoxymethylsphinganine commonly referred to as 1-deoxydihydroceramide (1-deoxyDHCer), is the N-acylated form of 1-deoxysphinganine,[1] a potent inhibitor of sphingolipid metabolism.

Działania biochem./fizjol.

Ceramide synthases (CerS) catalyzes the acylation of sphingoid bases using fatty acyl-CoA and its inhibition results in decrease of desoxymethylsphinganine (N-acylsphinganines (dihydroceramides)) levels and accumulation of sphinganine (Sa). Dihydroceramides (DHCer) are intermediates of ceramide biosynthesis.[2]

Opakowanie

5 mL Amber Glass Screw Cap Vial (860461P-1mg)

Informacje prawne

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3