809071

3-Propyl-3-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)-1,5-dioxaspiro[5.5]undecane-2,4-dione

• Wzór empiryczny (zapis Hilla): C₁₉H₁₇F₇O₄
• Numer CAS: 1632145-44-8
• Masa cząsteczkowa: 442.32
• NACRES: NA.22
• PubChem Substance ID: 329769136
• UNSPSC Code: 12352200
• MDL number: MFCD28359687
• Form: powder

Właściwości

• form: powder
• mp: 70 °C
• storage temp.: 2-8°C
• SMILES string: FC1=C(F)C(C(F)(F)F)=C(F)C(F)=C1C2(CCC)C(OC3(CCCCC3)OC2=O)=O
• InChI: 1S/C19H17F7O4/c1-2-6-18(15(27)29-17(30-16(18)28)7-4-3-5-8-17)9-11(20)13(22)10(19(24,25)26)14(23)12(9)21/h2-8H2,1H3
• InChI key: GQONRLKFRLHMSB-UHFFFAOYSA-N

Opis

General description

3-Propyl-3-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)-1,5-dioxaspiro[5.5]undecane-2,4-dione is a perfluorinated organic building block. It can be prepared by reacting octafluorotoluene, 3-propyl-1,5-dioxaspiro[5.5]-undecane-2,4-dione, N,N-diisopropylethylamine and CH₃CN.

Application

This compound undergoes cycloreversion to form the fluoro(hetero)aryl ketene, which undergoes efficient coupling with nucleophiles and allows rapid incorporation of highly fluorinated α-fluoro(hetero)aryl acetic acid derivatives.

Other Notes

Selective Perfluoro- and Polyfluoroarylation of Meldrum′s Acid

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Informacja o środkach bezpieczeństwa

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Klasa składowania: 12 - Non Combustible Liquids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable