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305995

2-Cyanoethyl N,N,N′,N′-tetraisopropylphosphorodiamidite

97%

Synonim(y):

Bis(diisopropylamino)(2-cyanoethoxy)phosphine

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Rozmiar/SKUDostępnośćCena netto
1 g
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395,00 zł
5 g
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1460,00 zł

Informacje o tej pozycji

Wzór liniowy:
{[(CH3)2CH]2N}2POCH2CH2CN
Numer CAS:
Masa cząsteczkowa:
301.41
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3590103
Assay:
97%
Form:
liquid

395,00 zł


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Quality Segment

assay

97%

form

liquid

refractive index

n20/D 1.470 (lit.)

bp

100 °C/0.5 mmHg (lit.)

density

0.949 g/mL at 25 °C (lit.)

functional group

amine, nitrile

storage temp.

−20°C

SMILES string

CC(C)N(C(C)C)P(OCCC#N)N(C(C)C)C(C)C

InChI

1S/C15H32N3OP/c1-12(2)17(13(3)4)20(19-11-9-10-16)18(14(5)6)15(7)8/h12-15H,9,11H2,1-8H3

InChI key

RKVHNYJPIXOHRW-UHFFFAOYSA-N

Application

2-Cyanoethyl N,N,N′,N′-tetraisopropylphosphordiamidite was used:
  • in preparation of prosphoramidite reagent, required for synthesis of 12-mer oligodeoxynucleotide
  • as phosphorylating agent in synthesis of 1,2-diacyl-sn-glycerophosphatidylserine
  • in situ preparation of deoxyribonucleoside phosphoramidites
  • in preparation of 2′-deoxy-2′-fluoro-3′-O-(β-cyanoethyl-N,N-diisopropylphosphoramidic)-5′-O-(4-methoxytrityl)-4′-thio-β-D-arabinouridine and 1-(3-O-(β-cyanoethyl-N,N-diisopropylphosphoramidic)-2-deoxy-2-fluoro-5-O-(4,4′-dimethoxytrityl)-4-thio-β-D-arabinofuranosyl)-thymine
  • as reagent for synthesizing phosphitylated nucleotides

Disclaimer

Supply conditions do not apply to the regions and states of Brazil: North, Northeast, Mato Grosso do Sul, Mato Grosso, and Rio Grande do Sul.
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Ta pozycja
779253779377727482
description

97%

description

~0.5 M in tert-butyl methyl ether, ≥95.0% (HPLC)

description

~0.5 M in tert-butyl methyl ether, ≥95.0% (HPLC)

description

~0.5 M in tert-butyl methyl ether, ≥95.0% (HPLC)

assay

97%

assay

≥95.0% (HPLC)

assay

≥95.0% (HPLC)

assay

≥95.0% (HPLC)

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

100

bp

100 °C/0.5 mmHg (lit.)

bp

-

bp

-

bp

-

density

0.949 g/mL at 25 °C (lit.)

density

-

density

-

density

-

form

liquid

form

liquid

form

liquid

form

liquid

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C


Piktogramy

FlameExclamation mark

Słowo ostrzegawcze

Warning

Kody zagrożeń

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Flam. Liq. 3 - Skin Sens. 1B

Klasa składowania

3 - Flammable liquids

Co się dzieje?

WGK 2

Temperatura zapłonu (°F)

119.3 °F - closed cup

Temperatura zapłonu (°C)

48.5 °C - closed cup

PPE (środki ochrony indywidualnej)

dust mask type N95 (US), Eyeshields, Gloves



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Certyfikaty analizy (CoA)

Lot/Batch Number

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Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. In 2-Cyanoethyl N,N,N′,N′-tetraisopropylphosphorodiamidite reagent is there any stabilizer is added! what is the stabilizer added for the storage of the above reagent.

    1 answer
    1. There is no stabilizer added, but the product is handled and stored under nitrogen due to its moisture sensitivity.

      Helpful?

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