287644

(1R,2R)-(−)-Pseudoephedrine

98%

• Synonim(y): α-(1-Methylaminoethyl)benzyl alcohol, (−)-ψ-Ephedrine, (−)-Pseudoephedrine, (1R,2R)-(−)-2-(Methylamino)-1-phenylpropanol, l-Pseudoephedrine
• Wzór liniowy: C₆H₅CH[CH(NHCH₃)CH₃]OH
• Numer CAS: 321-97-1
• Masa cząsteczkowa: 165.23
• UNSPSC Code: 12352116
• NACRES: NA.22
• PubChem Substance ID: 24857283
• EC Number: 206-292-8
• Beilstein/REAXYS Number: 2803417
• MDL number: MFCD00002203

Właściwości

• Quality Segment: 100
• assay: 98%
• form: solid
• optical activity: [α]20/D −51°, c = 0.6 in ethanol
• mp: 118-120 °C (lit.)
• functional group: amine, hydroxyl, phenyl
• SMILES string: CN[C@H](C)[C@H](O)c1ccccc1
• InChI: 1S/C10H15NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,10-12H,1-2H3/t8-,10+/m1/s1
• InChI key: KWGRBVOPPLSCSI-SCZZXKLOSA-N

Opis

General description

(1R,2R)-(-)-Pseudoephedrine is an enantiomer of ephedrine mainly used as a chiral auxiliary for asymmetric synthesis.

Application

(1R,2R)-(-)-Pseudoephedrine may be used in the preparation of chiral relay ligands, which can catalyze the addition of diethylzinc to aldehydes leading to the corresponding secondary alcohol. The immobilization of pseudoephedrine on Merrifield resin forms a chiral linker, which may be used for the asymmetric alkylation of amides via solid-phase approach.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS05,GHS07
• Słowo ostrzegawcze: Danger
• Kody zagrożeń: H302,H314,H317,H336
• Ostrzeżenia: P260 - P271 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3
• Narządy docelowe: Central nervous system
• Klasa składowania: 8A - Combustible corrosive hazardous materials
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• PPE (środki ochrony indywidualnej): dust mask type N95 (US), Eyeshields, Gloves