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21860

CDI

greener alternative

Bardziej ekologiczna alternatywa

≥97.0% (T), for peptide synthesis

Synonim(y):

1,1′-Carbonyldiimidazole

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Do Państwa/SKUDostępnośćCena netto
5 g
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204,00 zł
25 g
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559,00 zł
500 g
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751,00 zł
100 g
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1800,00 zł

Informacje o tej pozycji

Wzór empiryczny (zapis Hilla):
C7H6N4O
Numer CAS:
Masa cząsteczkowa:
162.15
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352115
EC Number:
208-488-9
MDL number:
Beilstein/REAXYS Number:
6826

204,00 zł


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Nazwa produktu

CDI, ≥97.0% (T)

Quality Segment

assay

≥97.0% (T)

form

solid

reaction suitability

reaction type: Carbonylations

greener alternative product characteristics

Designing Safer Chemicals
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

mp

115-122 °C, 117-122 °C (lit.)

application(s)

peptide synthesis

greener alternative category

storage temp.

2-8°C

SMILES string

O=C(n1ccnc1)n2ccnc2

InChI

1S/C7H6N4O/c12-7(10-3-1-8-5-10)11-4-2-9-6-11/h1-6H

InChI key

PFKFTWBEEFSNDU-UHFFFAOYSA-N

General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of the 12 Principles of Green Chemistry. 1,1′-carbonyldiimidazole (CDI) is an alternative to highly toxic insidious poison phosgene and thus aligns with the principle "Designing Safer Chemicals". Click here for more information.
CDI serves as a powerful coupling reagent in peptide synthesis and organic chemistry.

Application

CDI (1,1′-Carbonyldiimidazole) can be used:
  • In the activation of malonic acid derivatives to prepare carbonyl imidazoles by mild decarboxylation.
  • In the activation of cellulose membranes for the development of immunosensors.
  • In the synthesis of substituted 1,3-oxazolo[4,5-d] pyridazinones.
  • As a reagent for the conversion of various hydroxamic acids to isocyanates by Lossen rearrangement.
  • In the synthesis of 1,3,4-oxadiazole derivatives , and peptide thioesters in water.
  • As an acylation agent for the synthesis of carbamates.

Other Notes

Reactive reagent for the activation of acids as imidazolides: synthesis of esters, amides, ketones etc. Reagent for immobilizing enzymes and affinity ligands; Carbonyl-transfer reagent for the synthesis of various heterocycles, some recent applications
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Ta pozycja
115533T4069700746
CDI ≥97.0% (T)

Sigma-Aldrich

21860

CDI

CDI reagent grade

Sigma-Aldrich

115533

CDI

JC-1 powder or solid (Crystals)

Sigma-Aldrich

T4069

JC-1

description

≥97.0% (T)

description

reagent grade

description

powder or solid (Crystals)

description

-

form

solid

form

solid

form

powder or solid (Crystals)

form

solid

assay

≥97.0% (T)

assay

≥90.0% (proton, NMR)

assay

≥97%

assay

-

storage temp.

2-8°C

storage temp.

-

storage temp.

room temp

storage temp.

−20°C

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

100

mp

117-122 °C (lit.), 115-122 °C

mp

117-122 °C (lit.)

mp

-

mp

199-204 °C

application(s)

peptide synthesis

application(s)

peptide synthesis

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

-


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signalword

Danger

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1B - Skin Corr. 1C

Klasa składowania

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects



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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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