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4-Hydroxy-TEMPO

95%

Synonim(y):

4-Hydroxy-2,2,6,6-tetramethylpiperidine 1-oxyl, TEMPOL

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Rozmiar/SKUDostępnośćCena netto
1 g
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175,00 zł
5 g
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644,00 zł
25 g
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Informacje o tej pozycji

Wzór empiryczny (zapis Hilla):
C9H18NO2
Numer CAS:
Masa cząsteczkowa:
172.24
UNSPSC Code:
12352119
NACRES:
NA.22
PubChem Substance ID:
EC Number:
218-760-9
Beilstein/REAXYS Number:
1422990
MDL number:
Assay:
95%
Form:
solid

175,00 zł


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Quality Segment

assay

95%

form

solid

composition

Carbon content, 60.6-65.0% , Nitrogen content, 7.8-8.4%

mp

69-71 °C (lit.)

functional group

hydroxyl

storage temp.

2-8°C

SMILES string

CC1(C)CC(O)CC(C)(C)N1[O]

InChI

1S/C9H18NO2/c1-8(2)5-7(11)6-9(3,4)10(8)12/h7,11H,5-6H2,1-4H3

InChI key

UZFMOKQJFYMBGY-UHFFFAOYSA-N

General description

4-Hydroxy-TEMPO is a 4-substituted 2,2,6,6-tetramethylpiperidyl-1-oxy (TEMPO) derivative. It is a low-molecular weight compound and has been proposed as superoxide dismutase mimic.

Application

Spin label for studying biological compounds and polymers.
Spin label reagent used in the chatacterization of antagonist and agonist binding sites of NK1 receptor. Also used to measure reactive oxygen generation in heart muscle by electron spin resonance spectroscopy. Cells that overexpress CYP2E1 can be protected from arachidonic acid toxicity damage by TEMPOL.
A fluorous-tagged TEMPO derivative was prepared from the derived TEMPO propargylic ether and subsequent "click" reaction with a fluorous azide. This TEMPO derivative proved to be a highly effective catalyst in the oxidation of alcohols with bleach.
4-Hydroxy-TEMPO (HO-TEMPO) may be employed as catalyst for the oxidation of alcohols to the corresponding aldehydes. It may be employed for the preparation of TEMPO based polymer catalyst systems, which are useful for the Anelli oxidation of various primary alcohols. It may be used as starting reagent in the synthesis of 4-(2,2,6,6-tetramethyl-1-oxyl-4-piperidoxyl)butyl bromide.
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Ta pozycja
581500390380179485
description

95%

description

A stable, cell-permeable nitroxide that acts as a free radical scavenger and nitric oxide spin trap.

description

97%

description

-

assay

95%

assay

≥95% (HPLC)

assay

97%

assay

-

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

100

form

solid

form

powder, crystals

form

powder

form

solid

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

-

storage temp.

2-8°C

mp

69-71 °C (lit.)

mp

-

mp

143-145 °C (lit.)

mp

-

functional group

hydroxyl

functional group

-

functional group

-

functional group

ketone


signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - STOT RE 2 Oral

target_organs

Liver,spleen

Klasa składowania

11 - Combustible Solids

flash_point_f

294.8 °F - DIN 51758

flash_point_c

146 °C - DIN 51758

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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