Przejdź do zawartości
Merck

PTPRN

protein tyrosine phosphatase, receptor type, N

Synonimy:
IA-2, IA-2/PTP, IA2, ICA512, R-PTP-N
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(5798) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010]
  • Mouse(19275) protein tyrosine phosphatase, receptor type, N
  • Rat(116660) protein tyrosine phosphatase, receptor type, N
  • Domestic Rabbit(100355368) protein tyrosine phosphatase, receptor type, N
  • domestic cat(101100657) protein tyrosine phosphatase, receptor type, N
  • dog(478921) protein tyrosine phosphatase, receptor type, N
  • cow(286810) protein tyrosine phosphatase, receptor type, N
  • sheep(101113312) protein tyrosine phosphatase, receptor type, N
  • domestic guinea pig(100733759) protein tyrosine phosphatase, receptor type, N
  • naked mole-rat(101718650) protein tyrosine phosphatase, receptor type, N

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-PTPRN antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
dog, human, mouse, rabbit, rat
Zastosowanie
western blot
Monoclonal Anti-PTPRN antibody produced in mouse, clone 8E3, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
Anti-PTPRN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-PTPRN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
Anti-ICA 512/RESP18 Antibody, clone 1348-D29-1, ,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
western blot

Proteins

Numer produktu
Opis
Gatunek
PTPIA2 Active human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human PTPRN,
Gatunek
human
MISSION® esiRNA, targeting mouse Ptprn,
Gatunek
mouse