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NFATC1

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

Synonimy:
NF-ATC, NFAT2, NFATc
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(4772) Summary: The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes. [provided by RefSeq, Jul 2013]
  • Mouse(18018) nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
  • Rat(100361818) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • Zebrafish(568315) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • dog(483925) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • Domestic Rabbit(100352378) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • domestic guinea pig(100730044) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • cow(511224) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • sheep(101108097) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • naked mole-rat(101697946) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • Horse(100065378) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • chicken(420815) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • domestic cat(101101259) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

Custom & Knockdown Gene Products

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
2,2′:5′,2′′:5′′,2′′′-Quaterthiophene, 96%,
Gatunek
human, rat, mouse

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-NFATC1 (ab1) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
Przeciwciało anty-NFAT2, klon 4I9P10, królicze monoklonalne, ,
Reaktywność gatunkowa
mouse
Zastosowanie
western blot
Anty-NFATC1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
ChIP
immunofluorescence
Anti-NFATc1 Antibody, clone 1O16 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
affinity binding assay

immunocytochemistry

immunohistochemistry

western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
NFAT Inhibitor, >96% (HPLC), solid,
Gatunek
mouse, human
2,2′:5′,2′′:5′′,2′′′-Quaterthiophene, 96%,
Gatunek
human, rat, mouse

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Nfatc1,
Gatunek
mouse
MISSION® esiRNA, targeting human NFATC1,
Gatunek
human