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Merck

MAP2K6

mitogen-activated protein kinase kinase 6

Synonimy:
MAPKK6, MEK6, MKK6, PRKMK6, SAPKK-3, SAPKK3
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(5608) Summary: This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. [provided by RefSeq, Jul 2008]
  • Mouse(26399) mitogen-activated protein kinase kinase 6
  • Rat(114495) mitogen-activated protein kinase kinase 6
  • dog(480454) mitogen-activated protein kinase kinase 6
  • chicken(417445) mitogen-activated protein kinase kinase 6
  • Zebrafish(65239) mitogen-activated protein kinase kinase 6
  • domestic guinea pig(100731419) mitogen-activated protein kinase kinase 6
  • naked mole-rat(101703028) mitogen-activated protein kinase kinase 6
  • sheep(101115047) mitogen-activated protein kinase kinase 6
  • Domestic Rabbit(100355230) mitogen-activated protein kinase kinase 6
  • cow(286883) mitogen-activated protein kinase kinase 6
  • domestic cat(101089813) mitogen-activated protein kinase kinase 6
  • Horse(100053056) mitogen-activated protein kinase kinase 6

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-MKK6 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry

western blot
Anti-MAP2K6 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
western blot
Anti-MAP2K6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
immunohistochemistry

western blot
SAPK Pathway Explorer Antibody Minipack, Upstate®,
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-MAP2K6 antibody produced in mouse, clone 2F2, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunofluorescence

proximity ligation assay

western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
PD 98,059, solid,
Gatunek
human

Proteins

Numer produktu
Opis
Gatunek
MKK6 active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥80% (SDS-PAGE),
Gatunek
human
MKK6/SKK3, active human, ≥80% (SDS-PAGE), recombinant, expressed in E. coli, Maltose binding protein tagged, buffered aqueous solution,
Gatunek
human
MKK6/SKK3 Protein, inactive, 50 g, Unactive, recombinant human MKK6, amino acids 4-end, fused at the N-terminus to a Mal-E tag, for use in Kinase Assays.,
Gatunek
human
MKK6/SKK3 (S599D, T603D) Protein, active, 10 µg, Active, N-terminal MBP tagged, recombinant, human MKK6/SKK3 residues 4-end containing S599D & T603D mutations. For use in Kinase Assays.,
Gatunek
human
MKK6/SKK3 Protein, active, 10 µg, Active, N-terminal, maltose binding protein tagged, human MKK6/SKK3 fusion protein, amino acids 4-end. For use in Kinase Assays.,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human MAP2K6,
Gatunek
human
MISSION® esiRNA, targeting mouse Map2k6,
Gatunek
mouse