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GPX1

glutathione peroxidase 1

Synonimy:
GPXD, GSHPX1
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(2876) Summary: This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14775) glutathione peroxidase 1
  • Rat(24404) glutathione peroxidase 1
  • chicken(100857115) glutathione peroxidase 1
  • Thale Cress(817046) phospholipid hydroperoxide glutathione peroxidase 1
  • domestic cat(101083751) glutathione peroxidase 1
  • Domestic Rabbit(100009258) glutathione peroxidase 1
  • Horse(100053396) glutathione peroxidase 1
  • naked mole-rat(101710466) glutathione peroxidase 1
  • sheep(100820742) glutathione peroxidase 1
  • dog(442961) glutathione peroxidase 1
  • domestic guinea pig(100729115) glutathione peroxidase 1
  • cow(281209) glutathione peroxidase 1

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-GPX1 Antibody, clone 1J19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
canine, feline, human, monkey, porcine
Zastosowanie
immunocytochemistry
immunohistochemistry

western blot
Anti-Glutathione peroxidase 1 (ISO1) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human, pig
Zastosowanie
ELISA
immunohistochemistry

western blot
ANTI-GPX1 (C-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse
Zastosowanie
flow cytometry
immunofluorescence

immunohistochemistry

western blot
Anti-Gpx1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
bovine, mouse, rat
Zastosowanie
ELISA
western blot
Monoclonal ANTI-FLAG® M2-Peroxidase (HRP) antibody produced in mouse, clone M2, purified immunoglobulin, buffered aqueous glycerol solution,
Reaktywność gatunkowa
all
Zastosowanie
ELISA

Proteins

Numer produktu
Opis
Gatunek
GPX1 human, recombinant, expressed in E. coli, His tagged, >90% (SDS-PAGE),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human GPX1,
Gatunek
human