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Merck

GABRD

gamma-aminobutyric acid (GABA) A receptor, delta

Synonimy:
EIG10, EJM7, GEFSP5
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(2563) Summary: Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(14403) gamma-aminobutyric acid (GABA) A receptor, subunit delta
  • Rat(29689) gamma-aminobutyric acid (GABA) A receptor, delta
  • Zebrafish(571422) gamma-aminobutyric acid (GABA) A receptor, delta
  • chicken(770710) gamma-aminobutyric acid (GABA) A receptor, delta
  • cow(508711) gamma-aminobutyric acid (GABA) A receptor, delta
  • dog(489609) gamma-aminobutyric acid (GABA) A receptor, delta
  • sheep(101122539) gamma-aminobutyric acid (GABA) A receptor, delta
  • domestic cat(101087589) gamma-aminobutyric acid (GABA) A receptor, delta
  • domestic guinea pig(100735228) gamma-aminobutyric acid (GABA) A receptor, delta
  • naked mole-rat(101700143) gamma-aminobutyric acid (GABA) A receptor, delta

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Small Molecule - Agonist

Numer produktu
Opis
Gatunek
Oxazepam, ,
Gatunek
human
Meprobamate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Gatunek
human
Meprobamate, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Gatunek
human

Small Molecule - Allosteric Modulator

Numer produktu
Opis
Gatunek
Oxazepam, ,
Gatunek
human
Midazolam maleate salt, ,
Gatunek
human
Oxazepam, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Oxazepam for peak identification, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Triazolam, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
Flumazenil, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Ganaxolone, ≥98% (HPLC), solid,
Gatunek
human, mouse
2,6-Diisopropylphenol, 97%,
Gatunek
human
Flumazenil, >99% (HPLC), solid,
Gatunek
rat, human
5α-Pregnan-3α-ol-20-one, solid,
Gatunek
human, mouse, rat

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-GABRD antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, dog, human, mouse, rabbit
Zastosowanie
immunohistochemistry
western blot
Anti-GABRD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Gabrd,
Gatunek
mouse
MISSION® esiRNA, targeting human GABRD,
Gatunek
human