CYP1A1
cytochrome P450, family 1, subfamily A, polypeptide 1
Synonimy:
AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX
Gatunek:
Human CYP1A1 (1543), Mouse Cyp1a1 (13076), Rat Cyp1a1 (24296), sheep CYP1A1 (100170113), Horse CYP1A1 (100062285), domestic cat CYP1A1 (554347), cow CYP1A1 (282870), dog CYP1A1 (100686778), dog CYP1A1 (487648), domestic guinea pig Cyp1a1 (100135512)
Identyfikator UniProtKB:
Identyfikator genu:
- Human(1543) Summary: This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. [provided by RefSeq, Jul 2008]
- Mouse(13076) cytochrome P450, family 1, subfamily a, polypeptide 1
- Rat(24296) cytochrome P450, family 1, subfamily a, polypeptide 1
- sheep(100170113) cytochrome P4501A1
- Horse(100062285) cytochrome P450, family 1, subfamily A, polypeptide 1
- domestic cat(554347) cytochrome P450 1A1
- cow(282870) cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1
- dog(100686778) cytochrome P450, family 1, subfamily A, polypeptide 1
- dog(487648) cytochrome P450
- domestic guinea pig(100135512) cytochrome P450, family 1, subfamily a, polypeptide 1
- chicken(396051) cytochrome P450, family 1, subfamily A, polypeptide 1
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-CYP1A1 antibody produced in mouse, clone 6G5, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-CYP1A1 (AB3), affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot
Anti-CYP1A1 (AB2), affinity isolated antibody,
Reaktywność gatunkowa
bovine, guinea pig, horse, human, mouse, rabbit, rat, sheep
Zastosowanie
immunohistochemistry
western blot
western blot
Cell Lines
Numer produktu
Opis
Gatunek
Small Molecule - Inhibitor
Numer produktu
Opis
Gatunek
Proteins
Numer produktu
Opis
Gatunek
Cytochrome P450 human, 1A1 Isozyme Microsomes, with P450 Reductase, recombinant, expressed in baculovirus infected insect cells (BTI-TN-5B1-4),
Gatunek
human
esiRNA
Numer produktu
Opis
Gatunek