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CDK8

cyclin-dependent kinase 8

Synonimy:
K35
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(1024) Summary: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex, which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH), thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery. [provided by RefSeq, Jul 2008]
  • Mouse(264064) cyclin-dependent kinase 8
  • domestic guinea pig(100718250) cyclin-dependent kinase 8
  • naked mole-rat(101719987) cyclin-dependent kinase 8
  • sheep(101115551) cyclin-dependent kinase 8
  • Domestic Rabbit(100353845) cyclin-dependent kinase 8
  • domestic cat(101086278) cyclin-dependent kinase 8
  • Zebrafish(373868) cyclin-dependent kinase 8
  • cow(507149) cyclin-dependent kinase 8
  • dog(486035) cyclin-dependent kinase 8
  • chicken(428080) cyclin-dependent kinase 8
  • Horse(100050819) cyclin-dependent kinase 8
  • fruit fly(39157) Cyclin-dependent kinase 8

Custom & Knockdown Gene Products

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-CDK8 Antibody, clone 7L5X2, Rabbit Monoclonal, ,
Reaktywność gatunkowa
human, rat
Zastosowanie
western blot
ANTI-CDK8 antibody produced in mouse, clone 5H4, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
Anti-CDK8 antibody produced in rabbit, IgG fraction of antiserum,
Reaktywność gatunkowa
bovine, dog, horse, human, mouse, pig, rabbit
Zastosowanie
western blot
Anti-CDK8 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse
Zastosowanie
ELISA
western blot
Anti-CDK8 antibody produced in rabbit, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunoprecipitation (IP)
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Olomoucine, ≥98% (HPLC),
Gatunek
human, rat

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Cdk8,
Gatunek
mouse
MISSION® esiRNA, targeting human CDK8,
Gatunek
human