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Merck

CDK11A

cyclin-dependent kinase 11A

Synonimy:
CDC2L2, CDC2L3, CDK11-p110, CDK11-p46, CDK11-p58, PITSLRE, p58GTA
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(728642) Summary: This gene encodes a member of the p34Cdc2 protein kinase family. p34Cdc2 kinase family members are known to be essential for eukaryotic cell cycle control. This gene is in close proximity to CDC2L1, a nearly identical gene in the same chromosomal region. The gene loci including this gene, CDC2L1, as well as metalloprotease MMP21/22, consist of two identical, tandemly linked genomic regions, which are thought to be a part of the larger region that has been duplicated. This gene and CDC2L1 were shown to be deleted or altered frequently in neuroblastoma with amplified MYCN genes. The protein kinase encoded by this gene could be cleaved by caspases and was demonstrated to play roles in cell apoptosis. Many transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of only two have been determined so far. [provided by RefSeq, Jul 2008]
  • Horse(100033941) cyclin-dependent kinase 11A
  • dog(489591) cyclin-dependent kinase 11A
  • naked mole-rat(101714919) cyclin-dependent kinase 11A

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-CDK11A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-CDK11A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
Anti-CDK11, ,
Reaktywność gatunkowa
human, mouse
Zastosowanie
ChIP
western blot
Anti-CDK11A/CDK11B antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse
Zastosowanie
immunohistochemistry
western blot