BCR
breakpoint cluster region
Synonimy:
ALL, BCR1, CML, D22S11, D22S662, PHL
Gatunek:
Human BCR (613), Mouse Bcr (110279), Rat Bcr (309696), chicken BCR (416952), Zebrafish bcr (568320), dog BCR (607482), domestic cat BCR (101101671), cow BCR (789892), Domestic Rabbit BCR (100339436), domestic guinea pig Bcr (100718992)
Identyfikator UniProtKB:
Identyfikator genu:
- Human(613) Summary: A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(110279) breakpoint cluster region
- Rat(309696) breakpoint cluster region
- chicken(416952) breakpoint cluster region
- Zebrafish(568320) breakpoint cluster region
- dog(607482) breakpoint cluster region
- domestic cat(101101671) breakpoint cluster region
- cow(789892) breakpoint cluster region
- Domestic Rabbit(100339436) breakpoint cluster region
- domestic guinea pig(100718992) breakpoint cluster region
- naked mole-rat(101716702) breakpoint cluster region
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-phospho-BCR (pTyr177) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse
Zastosowanie
immunohistochemistry
western blot
western blot
Anti-phospho-Bcr (pTyr177) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
western blot
western blot
Przeciwciało anty-fosfo-BCR-Y177wytwarzane u królika, ,
Reaktywność gatunkowa
human, mouse
Zastosowanie
western blot
Anty-fosfo-Bcr(pTyr360), affinity isolated antibody,
Reaktywność gatunkowa
human, mouse
Zastosowanie
western blot
Anti-BCR (N-term) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
Cell Lines
Numer produktu
Opis
Gatunek
Proteins
Numer produktu
Opis
Gatunek
BCR (1-695), GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Gatunek
human