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Merck

AGTR1

angiotensin II receptor, type 1

Synonimy:
AG2S, AGTR1A, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, AT2R1A, AT2R1B, HAT1R
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(185) Summary: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Jul 2012]
  • naked mole-rat(101714068) angiotensin II receptor, type 1
  • Domestic Rabbit(100009164) angiotensin II receptor, type 1
  • domestic guinea pig(100192325) angiotensin II receptor, type 1
  • sheep(443107) angiotensin II receptor, type 1
  • dog(403836) angiotensin II receptor, type 1
  • chicken(396065) angiotensin II receptor, type 1
  • cow(281607) angiotensin II receptor, type 1
  • domestic cat(101082936) angiotensin II receptor, type 1

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Small Molecule - Agonist

Numer produktu
Opis
Gatunek
ProteoMass Angiotensin II MALDI-MS Standard, vial of 10 nmol,
Gatunek
human
[Val5]-Angiotensin II acetate salt hydrate, ≥95% (HPLC), powder,
Gatunek
mouse, human, rat
[Asn1, Val5]-Angiotensin II, ≥97% (HPLC),
Gatunek
mouse, human, rat

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
Valsartan, ≥98% (HPLC),
Gatunek
human
Candesartan cilexetil, ≥98% (HPLC),
Gatunek
human
Eprosartan mesylate, ≥98% (HPLC),
Gatunek
human
Losartan potassium, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Losartan potassium, ,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-AGTR1 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, dog, guinea pig, human, mouse, rabbit, rat, sheep
Zastosowanie
western blot
Anti-AGTR1/AT1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse
Zastosowanie
ELISA
western blot
Anti-AGTR1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-AT1 Receptor Antibody, Chemicon®, from rabbit,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Anti-AGTR1 Antibody, clone 1I12 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
bovine, canine, human, mouse, rat
Zastosowanie
affinity binding assay
immunocytochemistry

western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Captopril, ≥98% (HPLC), powder,
Gatunek
human, rat
2,2′:5′,2′′:5′′,2′′′-Quaterthiophene, 96%,
Gatunek
human, rat, mouse

Proteins

Numer produktu
Opis
Gatunek
ChemiSCREEN Human Angiotensin II Receptor, Type I Membrane Preparation, Human AT1 GPCR membrane preparation for Radioligand binding Assays & GTPγS binding.,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human AGTR1,
Gatunek
human