1463508

Nifedipine

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester
• Empirical Formula (Hill Notation): C₁₇H₁₈N₂O₆
• CAS Number: 21829-25-4
• Molecular Weight: 346.33
• NACRES: NA.24
• PubChem Substance ID: 329750558
• UNSPSC Code: 41116107
• EC Number: 244-598-3
• MDL number: MFCD00057326

Properties

• grade: pharmaceutical primary standard
• agency: USP
• API family: nifedipine
• manufacturer/tradename: USP
• application(s): pharmaceutical; pharmaceutical (small molecule)
• format: neat
• SMILES string: COC(=O)C1=C(C)NC(C)=C(C1c2ccccc2[N+]([O-])=O)C(=O)OC
• InChI: 1S/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8,15,18H,1-4H3
• InChI key: HYIMSNHJOBLJNT-UHFFFAOYSA-N
• Gene Information: human ... CACNA1C(775), CACNA1D(776), CACNA1F(778), CACNA1S(779)

Description

General description

Find answers to frequently asked questions on USP products in USP FAQs.

Application

Nifedipine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Nifedipine Capsules
• Nifedipine Extended-Release Tablets

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Codes: H302
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• Precautionary Statements: P264 - P270 - P301 + P312 - P501