The highest test point found is that the substance is soluble in DMSO at a concentration of 50 mg/ml.
481981
Nifedipine
≥98% (UV), L-type Ca2+ channel bocker, solid
Synonym(s):
Nifedipine, L-Type Calcium Channel Blocker III
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 250 mg | Check Cart for Availability | PLN 343.00 |
About This Item
Empirical Formula (Hill Notation):
C17H18N2O6
CAS Number:
Molecular Weight:
346.33
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (UV)
Form:
solid
Storage condition:
OK to freeze, protect from light
Product Name
Nifedipine, Relatively selective blocker of L-type Ca2+ channels.
description
Merck USA index - 14, 6528
Quality Segment
assay
≥98% (UV)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
yellow
solubility
DMSO: soluble, ethanol: soluble
shipped in
ambient
storage temp.
10-30°C
SMILES string
[N+](=O)([O-])c1c(cccc1)C2C(=C(NC(=C2C(=O)OC)C)C)C(=O)OC
InChI
1S/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8,15,18H,1-4H3
InChI key
HYIMSNHJOBLJNT-UHFFFAOYSA-N
General description
Relatively selective blocker of L-type Ca2+ channels. One of the most extensively studied blockers of 1,4-dihydropyridine-type Ca2+ channels, and a pharmacologically-useful vasodilator. Induces apoptosis in human glioblastoma cells.
Biochem/physiol Actions
Product does not compete with ATP.
Reversible: no
Cell permeable: no
Primary Target
L-type Ca2+ channels
L-type Ca2+ channels
Preparation Note
Following reconstitution, refrigerate (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Reid, K., et al. 1997. J. Pharmacol. Exp. Ther. 283, 993.
Kondo, S., et al. 1995. J. Neurosurg.82, 469.
Antkiewicz-Michaluk, L., et al. 1994. Eur. J. Pharmacol. 254, 9.
Calabresi, P., et al. 1994. J. Neurosci. 14, 4871.
Akman, M.S., et al. 1993. Endocrinology132, 1286.
Cirillo, M., et al. 1993. Circ. Res.72, 847.
Young, R.J., et al. 1993. Biochim. Biophys. Acta1146, 81.
Janis, R., et al. 1987. Adv. Drug Res.16, 311.
Kondo, S., et al. 1995. J. Neurosurg.82, 469.
Antkiewicz-Michaluk, L., et al. 1994. Eur. J. Pharmacol. 254, 9.
Calabresi, P., et al. 1994. J. Neurosci. 14, 4871.
Akman, M.S., et al. 1993. Endocrinology132, 1286.
Cirillo, M., et al. 1993. Circ. Res.72, 847.
Young, R.J., et al. 1993. Biochim. Biophys. Acta1146, 81.
Janis, R., et al. 1987. Adv. Drug Res.16, 311.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Harmful & Carcinogenic / Teratogenic (E)
1 of 1
This Item | |||
|---|---|---|---|
| assay ≥98% (UV) | assay - | assay - | assay - |
| form solid | form - | form - | form solid |
| manufacturer/tradename Calbiochem® | manufacturer/tradename EDQM | manufacturer/tradename - | manufacturer/tradename BP |
| Quality Level 100 | Quality Level - | Quality Level 300 | Quality Level - |
| storage temp. 10-30°C | storage temp. - | storage temp. 2-30°C | storage temp. 2-8°C |
| storage condition OK to freeze, protect from light | storage condition - | storage condition - | storage condition - |
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| 481981-250MG | 04055977183443 |
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