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Documentos

1279804

USP

Fluoxetina hydrochloride

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

(±)-N-metil-γ-[4-(trifluorometil)fenoxi]bencenopropanamina hydrochloride, LY-110,140 hydrochloride, Prozac®

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About This Item

Fórmula empírica (notación de Hill):
C17H18F3NO · HCl
Número de CAS:
56296-78-7
Peso molecular:
345.79
MDL number:
MFCD00214288
UNSPSC Code:
41116107
PubChem Substance ID:
329749876
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

fluoxetine

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CNCCC(C1=CC=CC=C1)OC2=CC=C(C(F)(F)F)C=C2.[H]Cl

InChI

1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H

InChI key

GIYXAJPCNFJEHY-UHFFFAOYSA-N

Gene Information

human ... SLC6A4(6532)

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Categorías relacionadas

Application

Fluoxetine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Fluoxetine Tablets
  • Fluoxetine Delayed-Release Capsules
  • Olanzapine and Fluoxetine Capsules
  • Fluoxetine Oral Solution
  • Fluoxetine Capsules

Biochem/physiol Actions

Inhibidor selectivo de la recaptación de serotonina; antidepresivo.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Legal Information

Se vende bajo licencia de Eli Lilly and Company.
Prozac is a registered trademark of Eli Lilly and Co.

related product

Referencia del producto
Descripción
Precios

F0253030

Fluoxetine impurity C, European Pharmacopoeia (EP) Reference Standard

1279826

Fluoxetine Related Compound B, United States Pharmacopeia (USP) Reference Standard

1279837

Fluoxetine Related Compound C, United States Pharmacopeia (USP) Reference Standard

1279815

Fluoxetine Related Compound A, United States Pharmacopeia (USP) Reference Standard

BP797

Fluoxetina hydrochloride, British Pharmacopoeia (BP) Reference Standard

PHR1953

Fluoxetine Related Compound C, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1952

Fluoxetine Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2041

Fluoxetine Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

Y0002201

Fluoxetine impurity A, CRS, European Pharmacopoeia (EP) Reference Standard

Y0002219

Fluoxetina hydrochloride, CRS, European Pharmacopoeia (EP) Reference Standard

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - STOT RE 2 - STOT SE 3

target_organs

Central nervous system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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R J Gonzalez-Rothi et al.
Chest, 107(6), 1763-1765 (1995-06-01)
We describe a patient who developed progressive dyspnea, lung infiltrates, and restrictive lung disease in association with the antidepressant fluoxetine hydrochloride (Prozac). The pathologic findings were consistent with hypersensitivity pneumonitis. An associated pulmonary phospholipidosis was also noted.
Paulina Jedynak et al.
Journal of psychiatric research, 56, 106-111 (2014-06-17)
The neurogenesis hypothesis of major depression has two main facets. One states that the illness results from decreased neurogenesis while the other claims that the very functioning of antidepressants depends on increased neurogenesis. In order to verify the latter, we
Kristie T Ota et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 40(3), 711-718 (2014-09-03)
Major depressive disorder (MDD) is a debilitating and widespread illness that exerts significant personal and socioeconomic consequences. Recent genetic and brain-imaging studies suggest that bicaudal C homolog 1 gene (BICC1), which codes for an RNA-binding protein, may be associated with
Sean C Godar et al.
Journal of psychiatric research, 56, 1-9 (2014-06-03)
The termination of serotonin (5-hydroxytryptamine, 5-HT) neurotransmission is regulated by its uptake by the 5-HT transporter (5-HTT), as well as its degradation by monoamine oxidase (MAO)-A. MAO-A deficiency results in a wide set of behavioral alterations, including perseverative behaviors and
Melody V Wu et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 39(8), 1861-1871 (2014-02-13)
Adult hippocampal neurogenesis is critically implicated in rodent models of stress and anxiety as well as behavioral effects of antidepressants. Whereas similar factors such as psychiatric disorder and antidepressant administration are correlated with hippocampal volume in humans, the relationship between
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