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SML2967

Sigma-Aldrich

Gp91ds-tat, scrambled trifluoroacetate

≥95% (HPLC)

Sinónimos:

Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Cys-Leu-Arg-Ile-Thr-Arg-Gln-Ser-Arg-NH2 trifluoroacetate, Gp91 ds-tat, scrambled trifluoroacetate, NADPH oxidase 2 docking sequence-tat trifluoroacetate, NOX2 ds-tat, scrambled trifluoroacetate, NOX2ds-tat, scrambled trifluoroacetate, RKKRRQRRR-CLRITRQSR-NH2 trifluoroacetate, scrambled Gp91phox docking sequence-tat trifluoroacetate, scrambled NOX2 docking sequence-tat trifluoroacetate

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About This Item

Fórmula empírica (notación de Hill):
C98H190N50O22S · xC2HF3O2
Peso molecular:
2452.94 (free base basis)
UNSPSC Code:
12352200
NACRES:
NA.77
En este momento no podemos mostrarle ni los precios ni la disponibilidad

Quality Level

100

assay

≥95% (HPLC)

form

film or powder

color

white to off-white

storage temp.

−20°C

Biochem/physiol Actions

Inactive control peptide for the NADPH oxidase inhibitor peptide gp91ds-tat (NOX2ds-tat). The control peptide is composed of a membrane-permeant HIV-1 Tat protein transduction domain sequence (aa49-57) N-terminal to a scrambled sequence of murine gp91phox (NOX2) aa86-94.
Scrambled inactive control peptide for the NADPH oxidase inhibitor peptide gp91ds-tat (NOX2ds-tat).

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
0000167012

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Dina Vara et al.
Haematologica, 104(9), 1879-1891 (2019-01-27)
The regulation of platelets by oxidants is critical for vascular health and may explain thrombotic complications in diseases such as diabetes and dementia, but remains poorly understood. Here, we describe a novel technique combining electron paramagnetic resonance spectroscopy and turbidimetry
F E Rey et al.
Circulation research, 89(5), 408-414 (2001-09-05)
We previously reported enhanced expression of the p67(phox) and gp91(phox) components of NAD(P)H oxidase in angiotensin (Ang) II-induced hypertension, suggesting de novo assembly in response to Ang II. To examine the direct involvement of NAD(P)H oxidases in Ang II-induced O(2)(-)
Boris Sabirzhanov et al.
Brain, behavior, and immunity, 80, 73-87 (2019-02-27)
NADPH oxidase (NOX2) is an enzyme that induces reactive oxygen species (ROS) and serves as a switch between the pro-inflammatory and neurorestorative microglial/macrophage phenotypes; such changes play an important role in neuropathic pain and motor dysfunction. Increased NOX2 expression after

Questions

  1. How to know the procedure of your product (drug code: SML2967) and other drugs

    1 answer

    1. Unfortunately, a protocol is not made readily available for this product. However, it may be helpful to review the publications located under the 'PEER REVIEWED PAPERS' section of the Product Detail Page. Please see the links below to review the listed citations:

      https://www.ahajournals.org/doi/10.1161/hh1701.096037

      https://doi.org/10.1371/journal.pone.0027039

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