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Merck
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L0636

Sigma-Aldrich

Lectin from Triticum vulgaris (wheat)

suitable for cell culture, BioReagent, lyophilized powder

Sinónimos:

WGA, Wheat germ agglutinin

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About This Item

Código UNSPSC:
12352202
NACRES:
NA.32

esterilidad

aseptically processed

Nivel de calidad

200

Línea del producto

BioReagent

Formulario

lyophilized powder

técnicas

cell culture | mammalian: suitable

impurezas

salt, essentially free

temp. de almacenamiento

2-8°C

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Descripción general

Lectin from Triticum vulgaris (wheat) is a dimeric glycoprotein of 36 kDa. It belongs to the family of chitin-binding proteins. Glycosylated precursor of lectin is synthesized in endoplasmic reticulum.

Aplicación

Lectin from Triticum vulgaris (wheat) has been used:
  • to conjugate with N-hydroxysuccinimide (NHS) dye
  • to inhibit nuclear import
  • to inhibit the nuclear pore of human cervical carcinoma HeLa and SiHa cells

Acciones bioquímicas o fisiológicas

Lectin from Triticum vulgaris (wheat) possessing four binding sites is specific for N-acetyl-d-glucosamine and N-acetyl-d-neuraminic acid (sialic acid) residues. Lectins also function as a fungicide. They also possess anti-nutritive effects.
WGA is not blood group specific but has an affinity for N-acetyl-β-D-glucosaminyl residues and N-acetyl-β-D-glucosamine oligomers. WGA contains no protein-bound carbohydrate.

Otras notas

Highly purified

Nota de preparación

Conjugates are prepared from affinity purified lectin.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
0000377325
0000371189
0000333158
0000371189
0000285398

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Super-multiplex vibrational imaging
Wei L, et al.
Nature, 544, 465-465 (2017)
Pengfei Zhang et al.
Chemical science, 13(43), 12760-12768 (2022-12-16)
Exosome analysis is a promising tool for clinical and biological research applications. However, detection and biomarker quantification of exosomes is technically challenging because they are small and highly heterogeneous. Here, we report an optical approach for imaging exosomes and quantifying
Effects of wheat germ agglutinin on human gastrointestinal epithelium: insights from an experimental model of immune/epithelial cell interaction
Dalla P, et al.
Toxicology and Applied Pharmacology, 237, 146-153 (2009)
Plant lectins: occurrence, biochemistry, functions and applications
Rudiger H and Gabius HJ
Glycoconjugate Journal, 18, 589-613 (2001)
Jonathan Welch et al.
Regulatory toxicology and pharmacology : RTP, 125, 105022-105022 (2021-08-02)
The aim of the study was to use multiple in vitro assays to assess the effects of a model irritant, sodium dodecyl sulphate (SDS) (≤10 mM (0.29 %, w/v)), on an in vitro model of the airway, MucilAir™. The use of MucilAir™
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Lectin Selection Guide: A Useful Guide for Selecting the Right Lectin

Find the right lectin for your research with our lectin selection guide, organized by lectin source/species, carbohydrate specificity, blood group specificity, and more.

Lectin Selection Guide: A Useful Guide for Selecting the Right Lectin

Find the right lectin for your research with our lectin selection guide, organized by lectin source/species, carbohydrate specificity, blood group specificity, and more.

Lectin Selection Guide: A Useful Guide for Selecting the Right Lectin

Find the right lectin for your research with our lectin selection guide, organized by lectin source/species, carbohydrate specificity, blood group specificity, and more.

Lectin Selection Guide: A Useful Guide for Selecting the Right Lectin

Find the right lectin for your research with our lectin selection guide, organized by lectin source/species, carbohydrate specificity, blood group specificity, and more.

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