A1520

α-Amylase Inhibitor

≥200 inhibitor U/mg protein (using porcine pancreatic α-amylase), ≥1000 inhibitor U/mg protein (using human salivary α-amylase), lyophilized powder

• Número MDL: MFCD00130475
• Código UNSPSC: 12352202
• NACRES: NA.77

Propiedades

• Nombre del producto: α-Amylase Inhibitor from Triticum aestivum (wheat seed), Type I, lyophilized powder
• origen biológico: Triticum estivum
• Nivel de calidad: 200
• tpo: Type I
• Formulario: lyophilized powder
• actividad específica: ≥1000 inhibitor U/mg protein (using human salivary α-amylase); ≥200 inhibitor U/mg protein (using porcine pancreatic α-amylase)
• composición: Protein, 35-65% biuret
• temp. de almacenamiento: −20°C

Descripción

Descripción general

α-Amylases are endoglycosidases, that are classified into glycosyl hydrolase family 13 (1-3).

Aplicación

α-Amylase Inhibitor from Triticum aestivum (wheat seed) has been used to determine its effects on salivary gland (SG) amylase activity. It has also been used to inhibit the activity from the extract from Bemisia tabaci.

Acciones bioquímicas o fisiológicas

α-Amylases can hydrolyze α-(1,4)-D-glycosidic linkages. It participates in the breakdown of starch and glycogen. Inhibiting this enzyme can be used as a strategy to treat dental caries, diabetes, obesity and periodontal diseases.

Competitive inhibitor of human salivary α-amylase. K_I = 2.9 nM, compared to a K_M of 5.9 mM (calculated per mole of α-1,4-linked maltose residues).

Definición de unidad

One unit will reduce the activity of two units of α-amylase (A0521) by 50% after pre-incubation at 25 °C.

Forma física

Lyophilized powder containing buffer salts as sodium phosphate.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)