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Merck

D0501

Supelco

4-Deoxypyridoxine hydrochloride

analytical standard

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About This Item

Fórmula empírica (notación de Hill):
C8H11NO2 · HCl
Número de CAS:
Peso molecular:
189.64
Número CE:
Número MDL:
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
NACRES:
NA.24

origen biológico

synthetic (organic)

Nivel de calidad

grado

analytical standard

Ensayo

≥98%

técnicas

HPLC: suitable
gas chromatography (GC): suitable

color

white to yellow

mp

263-265 °C

aplicaciones

forensics and toxicology
veterinary
vitamins, nutraceuticals, and natural products

Formato

neat

temp. de almacenamiento

−20°C

cadena SMILES

Cl.Cc1ncc(CO)c(C)c1O

InChI

1S/C8H11NO2.ClH/c1-5-7(4-10)3-9-6(2)8(5)11;/h3,10-11H,4H2,1-2H3;1H

Clave InChI

QZKKOQQIVLXUEI-UHFFFAOYSA-N

Descripción general

4-Deoxypyridoxine hydrochloride is a strong antagonist of vitamin B6.

Aplicación

4-Deoxypyridoxine hydrochloride analytical standard can be used as follows:
  • Development of a reversed-phase high-performance liquid chromatographic (RP-HPLC) method combined with mass spectrometric (MS) detection for the impurity analysis of metadoxine drug
  • As an internal standard in the ultra- and high- performance liquid chromatographic analysis of pyridoxine in multivitamin tablet samples coupled with UV, mass spectrometric, and fluorescence detector

Otras notas

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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J Scountzou et al.
Immunopharmacology and immunotoxicology, 11(4), 657-666 (1989-01-01)
We studied the effect of pyridoxine deficiency state on the responses of human lymphocytes to certain mitogenic factors. Deoxypyridoxine (DB6), a potent pyridoxine antagonist, considerably inhibited Bromodeoxyuridine (BrdU) incorporation into the newly synthesized DNA of lymphocytes cultured with Phytohemagglutinin (PHA)
A Trakatellis et al.
Postgraduate medical journal, 68 Suppl 1, S70-S77 (1992-01-01)
Measurements of serine hydroxymethyltransferase (SHMT) in resting lymphocyte cultures showed that the level of activity of this enzyme was very low. Under the influence of mitogenic stimuli serine hydroxymethyl-transferase activity was induced 5-20-fold. Addition in the cultures of 4-deoxypyridoxine, a
HPLC analysis of vitamin B6 in foods
Ollilainen, V-M
Agricultural and food science, 8(6), 515-619 (1999)
Hong Chen et al.
Fish & shellfish immunology, 19(3), 241-252 (2005-04-12)
A feeding experiment was conducted to investigate the effects of dietary pyridoxine (PN) on the immune responses of abalone, Haliotis discus hannai Ino. Purified diets supplemented with 0, 40, 800 mg PN kg(-1) or 80 mg kg(-1) of 4-deoxypyridoxine (PN
M Lorenzato et al.
Methods and findings in experimental and clinical pharmacology, 9(10), 649-656 (1987-10-01)
The study was performed with isolated perfused isovolumic rat hearts. After a 40 min stabilization period, the effect of 4-deoxypyridoxine (DOP) 10(-5) M was studied with 3 Glc concentrations: 0, 3.3 and 11 mM. DOP was perfused during a 20

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