539142

Proteasome Substrate III, Fluorogenic

≥98% (HPLC), amorphous solid, proteasome substrate, Calbiochem^®

• Sinónimos: Proteasome Substrate III, Fluorogenic, Suc-LLVY-AMC, Chymotrypsin Substrate III, Fluorogenic
• Fórmula empírica (notación de Hill): C₄₀H₅₃N₅O₁₀
• Peso molecular: 763.88
• UNSPSC Code: 12352200
• NACRES: NA.77

Propiedades

• product name: Proteasome Substrate III, Fluorogenic, Proteasome Substrate III, Fluorogenic, is a substrate for proteasome. Also acts as a substrate for calpain, chymotrypsin, and ingensin.
• Quality Level: 100
• assay: ≥98% (HPLC)
• form: amorphous solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; protect from light
• color: white
• solubility: DMSO: 50 mg/mL
• fluorescence: λ_ex ~380 nm; λ_em ~460 nm
• shipped in: ambient
• storage temp.: −20°C

Descripción

General description

Fluorogenic proteasome substrate. Also acts as a substrate for calpain, chymotrypsin, and ingensin.

Specificity

Inhibits serine proteases and cysteine proteases.

Biochem/physiol Actions

Cell permeable: no

Primary Target
Proteasome

Product does not compete with ATP.

Reversible: no

Warning

Toxicity: Standard Handling (A)

Sequence

Suc-Leu-Leu-Val-Tyr-AMC

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Other Notes

Anderson, M., et al. 1999. Exp. Eye Res.69, 129.
Rock, K.L., et al. 1994. Cell 78, 761.
Tsubuki, S., et al. 1993. Biochem. Biophys. Res. Commun.196, 1195.
Sasaki, T., et al. 1984. J. Biol. Chem. 259, 12489.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable