48912-U

ProClin^™ 300

ProClin^™ preservative for use in IVD manufacturing, pkg of 50 mL, CMIT/MIT 3 %

• Sinónimos: 3% solution of 5-chloro-2-methyl-4-isothiazolin-3-one and 2-Methyl-4-isothiazolin-3-one
• Código UNSPSC: 12352201
• NACRES: NA.21

Propiedades

• Formulario: liquid
• caducidad: 3 yr
• contiene: Alkyl Carboxylate
• composición: CMIT/MIT, 3%
• envase: pkg of 50 mL
• Parámetros: <45 °C operating temperature
• color: colorless to light yellow
• Matriz: Modified glycol
• Intervalo de pH operativo: 2.5-8.5
• pH: 4.1 (100 g/L)
• bp: 189 °C
• mp: -40 °C
• solubilidad: water: soluble
• densidad: 1.03 g/cm³

Descripción

Descripción general

ProClin^™ preservatives are water-soluble preparations of biocides that are generally used to increase the shelf life of reagents. ProClin^™ 300 comprises of 3% of 5-chloro-2-methyl-4-isothiazolin-3-one (CMIT) and 2-methyl-4-isothiazloin-3-one (MIT) in a salt-free proprietary glycol containing an alkly carboxylate stabilizer. It has a recommended working pH range as 2.5 - 8.5.

Aplicación

For use in IVD Manufacturing

ProClin^™ 300 is suitable for preparation of different buffers like ELISA buffer, sample and substrate dilution buffers for Single-Molecule Arrays (Simoa assay) and Immunoenzymatic assay. Additionally, Proclin^™ may be used in preparing storage buffer to store beads coupled with coronavirus nucleocapsid protein for the serological multiplex assay.

ProClin^™ biocides preservatives are immediately microstatic upon contact with microbial organisms as a result of their ability to quickly penetrate cell membranes and inhibit specific enzymes crucial to cellular respiration. Multiple specific sites of ProClin^™ toxicity prevent microorganisms from developing high levels of resistance, making ProClin^™ highly efficient even over extended storage periods of your IVD components.

Acciones bioquímicas o fisiológicas

ProClin^™ products contain active substances like CMIT and MIT which inhibit the Krebs cycle at four different check points, the enzymes pyruvate dehydrogenase, α-ketoglutarate dehydrogenase, succinate dehydrogenase, and NADH dehydrogenase. The inhibition of Krebs cycle leads to effective broad-spectrum biocidal activity against bacteria, fungi, and yeast.

Información legal

ProClin is a trademark of LANXESS Corp.

Cláusula de descargo de responsabilidad

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada′s Pest Management Regulatory Agency, Turkey′s Biocidal Products Regulation, Korea′s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

Información de seguridad

• Pictogramas: GHS05,GHS07,GHS09
• Palabra de señalización: Danger
• Frases de peligro: H302 + H332,H314,H317,H410
• Consejos de prudencia: P273 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Clasificaciones de peligro: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1
• Código de clase de almacenamiento: 8A - Combustible corrosive hazardous materials
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): 244.4 °F - closed cup
• Punto de inflamabilidad (°C): 118 °C - closed cup
• Equipo de protección personal: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter