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Merck

324868

Sigma-Aldrich

Potassium trimethylsilanolate

90%, technical grade

Sinónimos:

Trimethylsilanol potassium salt

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About This Item

Fórmula lineal:
(CH3)3SiOK
Número de CAS:
Peso molecular:
128.29
Beilstein:
3560282
Número CE:
Número MDL:
Código UNSPSC:
12352302
ID de la sustancia en PubChem:
NACRES:
NA.22
En este momento no podemos mostrarle ni los precios ni la disponibilidad

grado

technical grade

Nivel de calidad

Ensayo

90%

Formulario

powder

concentración

≤100%

mp

135-138 °C (lit.)
135-138 °C

cadena SMILES

[K+].C[Si](C)(C)[O-]
[K+].C[Si](C)(C)[O-]

InChI

1S/C3H9OSi.K/c1-5(2,3)4;/h1-3H3;/q-1;+1
1S/C3H9OSi.K/c1-5(2,3)4;/h1-3H3;/q-1;+1

Clave InChI

LBKJNHPKYFYCLL-UHFFFAOYSA-N
LBKJNHPKYFYCLL-UHFFFAOYSA-N

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Categorías relacionadas

Aplicación

Potassium trimethylsilanolate can be used as a reagent in the:
  • Hydrolysis of nitriles to primary amides.[1]
  • Conversion of esters to carboxylic acids,[2] and dialkyl phosphonates to their monoalkyl phosphonates.[3]
  • Synthesis of E-alkenes,[4] and nitrocefin.[5]


It can also be used as a coupling promoter in cross-coupling reaction of aliphatic alkynylsilanols with aryl iodides.[6]

Pictogramas

Corrosion

Palabra de señalización

Danger

Frases de peligro

Clasificaciones de peligro

Skin Corr. 1B

Código de clase de almacenamiento

8A - Combustible corrosive hazardous materials

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Certificados de análisis (COA)

Lot/Batch Number

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Visite la Librería de documentos

Tetrahedron Letters, 25, 5831-5831 (1984)
A practical synthesis of nitrocefin
Lee M, et al.
The Journal of Organic Chemistry, 70(1), 367-369 (2005)
Cross-coupling of alkynylsilanols with aryl halides promoted by potassium trimethylsilanolate
Denmark SE and Tymonko SA
The Journal of Organic Chemistry, 68(23), 9151-9154 (2003)
Scope and limitations of sodium and potassium trimethylsilanolate as reagents for conversion of esters to carboxylic acids
Lovric M, et al.
Croatica Chemica Acta. Arhiv Za Kemiju, 80(1), 109-115 (2007)
Potassium trimethylsilanolate mediated hydrolysis of nitriles to primary amides
Merchant KJ
Tetrahedron Letters, 41(19), 3747-3749 (2000)

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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