SAB4504099

Anti-phospho-PKC-pan (pThr⁴⁹⁷) antibody produced in rabbit

affinity isolated antibody

• Sinónimos: Anti-PKCL, Anti-PRKCL, Anti-nPKC-eta
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 76 kDa
• species reactivity: rat, mouse, human
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:40000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI accession no.: P05129; P05771; P17252; P24723; Q02156; Q04759; Q05513; Q05655
• UniProt accession no.: P24723
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pThr497)
• Gene Information: human ... PRKCA(5578) , PRKCB(5579) , PRKCD(5580) , PRKCE(5581) , PRKCG(5582) , PRKCH(5583) , PRKCQ(5588) , PRKCZ(5590)

Descripción

General description

Protein kinase C is a member of the cAMP-dependent, cGMP-dependent, and protein kinase C (AGC) superfamily of protein kinases. It has more than14 isoforms. A catalytic domain with an ATP binding site and a substrate-binding site is found in all PKC isoforms.

Immunogen

The antiserum was produced against synthesized peptide derived from human PKC-pan around the phosphorylation site of Thr497.

Immunogen Range: 623-672

Application

Anti-phospho-PKC-pan (pThr497) antibody produced in rabbit has been used in western blot analysis (1:500).

Biochem/physiol Actions

Protein kinase Cs (PKCs) are involved in the growth and function of the gastrointestinal tract and the immune response. PKCs regulates cyclins, cyclin-dependent kinases (cdks), cdk inhibitors, and cell division cycle 25 (cdc25) phosphatases.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable