S0189
Stemline® Hematopoietic Stem Cell Expansion Medium
suitable for, Without L-glutamine, liquid, sterile-filtered, suitable for cell culture
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sterility
sterile-filtered
form
liquid
technique(s)
cell culture | mammalian: suitable
suitability
suitable for
shipped in
wet ice
storage temp.
2-8°C
General description
Developed to promote the optimal expansion of human hematopoietic stem cells (HSC) from bone marrow, mobilized peripheral blood, and cord blood, Stemline Hematopoietic Stem Cell Expansion Medium demonstrates higher total nucleated cell (TNC) fold increases than other commercially available serum-free media formulations. Additionally, colony-forming unit (CFU) assays indicate that CD34+ hematopoietic stem cells grown in Stemline media demonstrate significantly greater expansion of bother early (HPP-CFC) and late (GM-CFC) progenitor populations when compared to those grown in alternative media. Human cord blood cells expanded in Stemline Media demonstrate impressive self-revewal when transplanted into immunodeficient NOC/SCID mice, illustrating Stemline′s utility in true functional trial.
Stemline Hematopoietic Stem Cell Expansion Medium free of serum and all other animal-derived components with the exception of human serum albumin and cholesterol. This exclusion increases performance consistency and elimates safety risks associated with potential adventitious agents.
Produced in a GMP state-of-the-art facility, Stemline Hematopoietic Stem Cell Expansion Medium is clearly an excellent choice for your HSC applications.
Stemline Hematopoietic Stem Cell Expansion Medium free of serum and all other animal-derived components with the exception of human serum albumin and cholesterol. This exclusion increases performance consistency and elimates safety risks associated with potential adventitious agents.
Produced in a GMP state-of-the-art facility, Stemline Hematopoietic Stem Cell Expansion Medium is clearly an excellent choice for your HSC applications.
Application
Intended for the expansion of CD 34+ progenitors derived from bone marrow, mobilized peripheral blood and cord blood.
Reconstitution
Must be supplemented with growth factors and cytokines according to individual user protocols.
Legal Information
Stemline is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Haiming Chen et al.
British journal of haematology, 192(3), 568-576 (2020-12-21)
Multiple myeloma (MM) tumour cells evade host immunity through a variety of mechanisms, which may potentially include the programmed cell death ligand-1 (PD-L1):programmed cell death protein-1 (PD-1) axis. This interaction contributes to the immunosuppressive bone marrow (BM) microenvironment, ultimately leading
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