SML3208

CPYPP

≥98% (HPLC)

• Sinónimos: 4-[3′-(2′′-chlorophenyl)-2′-propen-1′-ylidene]-1-phenyl-3,5-pyrazolidinedione
• Fórmula empírica (notación de Hill): C₁₈H₁₃ClN₂O₂
• Número de CAS: 310460-39-0
• Peso molecular: 324.76
• Número MDL: MFCD00980987
• Código UNSPSC: 51111800
• NACRES: NA.77

Propiedades

• Nivel de calidad: 100
• Ensayo: ≥98% (HPLC)
• Formulario: powder
• color: orange to dark red
• solubilidad: DMSO: 2 mg/mL, clear
• temp. de almacenamiento: −20°C
• cadena SMILES: Clc1c(cccc1)C=CC=C2C(=O)N(NC2=O)c3ccccc3
• InChI: 1S/C18H13ClN2O2/c19-16-12-5-4-7-13(16)8-6-11-15-17(22)20-21(18(15)23)14-9-2-1-3-10-14/h1-12H,(H,20,22)
• Clave InChI: VVZJFICTTKPNCK-UHFFFAOYSA-N

Descripción

Acciones bioquímicas o fisiológicas

CPYPP is a cell permeable potent and selective reversible inhibitor of DOCK2 that binds to DOCK2 DHR-2 domain. CPYPP is a DOCK2-Rac1 interaction inhibitor. It also inhibits DOCK1 and DOCK5. CPYPP potently inhibits metastatic spread of aggressive ROBO1deficient prostate cancer cells through the vasculature of transgenic Zebrafish model.

cell permeable potent and selective reversible inhibitor of DOCK2 that binds to DOCK2 DHR-2 domain

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids