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Key Documents

O1641

Sigma-Aldrich

Ovalbumin (323-339) (chicken, Japanese quail)

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.26

assay

97-100% (HPLC)

Quality Level

form

lyophilized powder

composition

peptide content, 65-100%

color

white

solubility

water, double-distilled: soluble

storage temp.

−20°C

Amino Acid Sequence

H-Ile-Ser-Gln-Ala-Val-His-Ala-Ala-His-Ala-Glu-Ile-Asn-Glu-Ala-Gly-Arg-OH

General description

Ovalbumin (323-339) is an egg white protein surrounded by B-cell epitopes, which are bound by specific IgE antibodies. In addition to this, it also contains CD4+ T cell epitopes.
The peptide is a major MHC class II-restricted T-cell epitope of Ovalbumin which is used for studies of immunological allergic responses such as asthma, food allergy and more..

Application

Ovalbumin (323-339) (chicken, Japanese quail) has been used to induce allergic asthma in mice.

Biochem/physiol Actions

Ovalbumin (OVA) peptide 323-339 mediates 25–35% of T-cell response to intact OVA in isolated BALB/c mouse. OVA 323-339 has been widely used to determine the characteristics of class II major histocompatibility complex (MHC)-peptide binding and T-cell activation.
With the help of two functionally distinct registers ovalbumin (323-339) peptide can bind to histocompatibility complex class II I-A(d) protein.

Physical form

Lyophilized from 0.1% aqueous TFA

Other Notes

Lyophilized from 0.1% TFA in H2O

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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