Saltar al contenido
Merck

L5768

Sigma-Aldrich

Lanosterol

≥93%, powder

Sinónimos:

3β-Hydroxy-8,24-lanostadiene, 8,24-Lanostadien-3β-ol

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización

Seleccione un Tamaño

1 MG
MXP 2,702.00
5 MG
MXP 9,558.00

MXP 2,702.00


Fecha estimada de envío17 de abril de 2025


Solicitar un pedido a granel

Seleccione un Tamaño

Cambiar Vistas
1 MG
MXP 2,702.00
5 MG
MXP 9,558.00

About This Item

Fórmula empírica (notación de Hill):
C30H50O
Número de CAS:
Peso molecular:
426.72
EC Number:
MDL number:
UNSPSC Code:
12352211
PubChem Substance ID:
NACRES:
NA.77

MXP 2,702.00


Fecha estimada de envío17 de abril de 2025


Solicitar un pedido a granel

Quality Level

assay

≥93%

form

powder

color

white to off-white

storage temp.

−20°C

SMILES string

[H][C@@]1(CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](O)C(C)(C)[C@]4([H])CC3)[C@H](C)CC\C=C(/C)C

InChI

1S/C30H50O/c1-20(2)10-9-11-21(3)22-14-18-30(8)24-12-13-25-27(4,5)26(31)16-17-28(25,6)23(24)15-19-29(22,30)7/h10,21-22,25-26,31H,9,11-19H2,1-8H3/t21-,22-,25+,26+,28-,29-,30+/m1/s1

InChI key

CAHGCLMLTWQZNJ-BQNIITSRSA-N

¿Está buscando productos similares? Visita Guía de comparación de productos

Categorías relacionadas

General description

Lanosterol, an amphipathic molecule, that is produced by lanosterol synthase (LSS). It is enriched in the lens.[1]

Application

Lanosterol has been used:
  • as a standard in HPLC for the quantification in testis samples[2]
  • in S-adenosyl-L-methionine:Δ24-sterol-C-methyltransferase (SMT) assay[3]
  • to treat wild-type cells growing in rich medium to know its effects on Sre1 protein[4]

Biochem/physiol Actions

Cholesterol precursor sterol.
Lanosterol serves as an endogenous selective modulator of macrophage immunity.[5]

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number

¿No ve la versión correcta?

Si necesita una versión concreta, puede buscar un certificado específico por el número de lote.

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Los clientes también vieron

Ergosterol regulates sterol regulatory element binding protein (SREBP) cleavage in fission yeast
Porter J R, et al.
The Journal of Biological Chemistry, 285(52), 41051-41061 (2010)
Ying-Chi Du et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 19(8-9), 788-796 (2012-04-21)
Antrodia camphorata (AC) is a native Taiwanese mushroom which is used in Asian folk medicine as a chemopreventive agent. The triterpenoid-rich fraction (FEA) was obtained from the ethanolic extract of AC and characterized by high performance liquid chromatography (HPLC). FEA
Lanosterol modulates TLR4-mediated innate immune responses in macrophages
Araldi E, et al.
Testing, 19(13), 2743-2755 (2017)
Joanna L Sharman et al.
Nucleic acids research, 41(Database issue), D1083-D1088 (2012-10-23)
The International Union of Basic and Clinical Pharmacology (IUPHAR) database, IUPHAR-DB (http://www.iuphar-db.org) is an open access, online database providing detailed, expert-driven annotation of the primary literature on human and rodent receptors and other drug targets, together with the substances that
Lorena Fernández-Cabezón et al.
Frontiers in microbiology, 9, 958-958 (2018-06-06)
Nowadays steroid manufacturing occupies a prominent place in the pharmaceutical industry with an annual global market over $10 billion. The synthesis of steroidal active pharmaceutical ingredients (APIs) such as sex hormones (estrogens, androgens, and progestogens) and corticosteroids is currently performed

Artículos

Cholesterol biosynthesis starts in the hepatic endoplasmic reticulum with acetyl-CoA, yielding 3-hydroxy-3-methylglutaryl-CoA via HMG-CoA synthase.

Discover Bioactive Small Molecules for Lipid Signaling Research

Questions

1–2 of 2 Questions  
  1. How to prepare this product for cell experiments?

    1 answer
    1. The product has not been tested for use in cell culture, and its solubility has been tested at 100 mg/mL in chloroform.

      Helpful?

  2. How to prepare this product for cell experiments?

    1 answer
    1. This product is not tested for use in cell culture. The solubility is tested at 100 mg/mL in Chloroform. See the link below to a publication that may be helpful.
      https://www.sciencedirect.com/science/article/pii/S0167488919302253

      Helpful?

Reviews

No rating value

Active Filters

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico