SML0629

Mitochondrial Fusion Promoter M1

≥95% (HPLC), powder

• Synonym(s): (E)-4-Chloro-2-(1-(2-(2,4,6-trichlorophenyl)hydrazono)ethyl)phenol, 1-(5-Chloro-2-hydroxyphenyl)-ethanone 2-(2,4,6-trichlorophenyl)hydrazone
• Empirical Formula (Hill Notation): C₁₄H₁₀Cl₄N₂O
• CAS Number: 219315-22-7
• Molecular Weight: 364.05
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥95% (HPLC)
• Form: powder

Properties

• Product Name: Mitochondrial Fusion Promoter M1, ≥95% (HPLC)
• Quality Segment: 100
• assay: ≥95% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 10 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: Clc1c(c(cc(c1)Cl)Cl)NNC(=C)c2c(ccc(c2)Cl)O
• InChI key: WMAGOVJOXMBLHY-UHFFFAOYSA-N

Description

Application

Mitochondrial Fusion Promoter M1 has been used as a fusion promoter:

• to study its effects on peroxisome proliferator-activated receptor-γ coactivator (PGC)-1α expression in breast cancer cells[1]
• to study the link between nucleoside diphosphate kinase 3 (NME3)-regulated mitochondrial fluctuations and stability of genome in NME3 knockdown cells[2]
• to study its effects on mitochondrial fusion in neuronal cells[3]

Biochem/physiol Actions

Mitochondrial Fusion Promoter M1 is a cell permeable hydrazone that enhances mitochondrial fusion.

Mitochondrial Fusion Promoter M1 is a cell permeable hydrazone that enhances mitochondrial fusion. M1 protects cells from mitochondrial fragmentation associated cell death. Mitochondrial Fusion Promoter M1 does not interfere with endoplasmic reticula (ER) and lysosomes morphology.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable