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C6154

Z-Gln-Gly

γ-glutamyl donor substrate

Synonym(s):

N2-[(phenylmethoxy)carbonyl]-L-glutaminyl-glycine

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About This Item

Empirical Formula (Hill Notation):
C15H19N3O6
CAS Number:
6610-42-0
Molecular Weight:
337.33
NACRES:
NA.26
PubChem Substance ID:
24892841
UNSPSC Code:
12352209
MDL number:
MFCD00055926
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Quality Segment

200

form

powder

storage temp.

−20°C

SMILES string

NC(=O)CCC(NC(=O)OCc1ccccc1)C(=O)NCC(O)=O

InChI

1S/C15H19N3O6/c16-12(19)7-6-11(14(22)17-8-13(20)21)18-15(23)24-9-10-4-2-1-3-5-10/h1-5,11H,6-9H2,(H2,16,19)(H,17,22)(H,18,23)(H,20,21)

InChI key

SOUXAAOTONMPRY-UHFFFAOYSA-N

Application

γ-Glutamyl donor substrate used in spectrophotometric determination of transglutaminase (TGase) activity.[1][2] Z-Gln-Gly was used to enzymatically synthesize N-linked neoglycoproteins.[3]

Biochem/physiol Actions

N-Benzyloxycarbonyl-L-Glutaminylglycine (Z-Gln-Gly, Z-QG) is used as a substrate to differentiate and characterize transglutaminase(s) (TGase) that catalyzes the post-translational covalent cross-linking of Gln- and Lys-containing peptides. Z-QG supports glutamyl-level cross-linking applications thruough surface modification.

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This Item
P3501A0878P4510
Z-Gln-Gly γ-glutamyl donor substrate

Sigma-Aldrich

C6154

Z-Gln-Gly

Phe-Gly-Gly

Sigma-Aldrich

P3501

Phe-Gly-Gly

Ala-Gly

Sigma-Aldrich

A0878

Ala-Gly

Poly-ε-Cbz-L-lysine mol wt 500-4,000

Sigma-Aldrich

P4510

Poly-ε-Cbz-L-lysine

form

powder

form

powder

form

powder

form

powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

200

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM7966
BCCL3931
BCCH9653
BCCH3476
BCCD7504

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Global Trade Item Number

SKUGTIN
C6154-1G04061833510872

Questions

  1. Qual è la massima solubilità in H2O del composto Z-Gln-Gly cod.C6154?

    1 answer

    1. This product is tested for solubility at 50 mg/mL in 1 M NaOH. The solubility in water has not been determined.

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