68783

Licochalcone A

≥96.0% (HPLC)

• Synonym(s): (E)-3-[5-(1,1-Dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-2-propen-1-one, 4′,4-Dihydroxy-3-α,α-dimethylallyl-6-methoxychalcone
• Empirical Formula (Hill Notation): C₂₁H₂₂O₄
• CAS Number: 58749-22-7
• Molecular Weight: 338.40
• UNSPSC Code: 41116107
• NACRES: NA.77
• PubChem Substance ID: 329761160
• MDL number: MFCD01417903
• Beilstein/REAXYS Number: 4534154
• Assay: ≥96.0% (HPLC)
• Form: powder

Properties

• Quality Segment: 100
• assay: ≥96.0% (HPLC)
• form: powder
• storage temp.: −20°C
• SMILES string: COc1cc(O)c(cc1\C=C\C(=O)c2ccc(O)cc2)C(C)(C)C=C
• InChI: 1S/C21H22O4/c1-5-21(2,3)17-12-15(20(25-4)13-19(17)24)8-11-18(23)14-6-9-16(22)10-7-14/h5-13,22,24H,1H2,2-4H3/b11-8+
• InChI key: KAZSKMJFUPEHHW-DHZHZOJOSA-N

Description

General description

Licochalcone A is a potent membrane-active agent that transforms normal erythrocytes into echinocytes.[1] A novel flavanoid which has demonstrated significant antitumor activity.[2]

Biochem/physiol Actions

Inhibits vegetative growth of spore-forming bacteria, B. subtilis and other food-contaminating microorganisms.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302 + H312 + H332
• pcodes: P280 - P301 + P312 + P330 - P302 + P352 + P312 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves