If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
16758
Poloxamer 407
purified, non-ionic
Synonym(s):
Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)
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About This Item
Quality Segment
form
powder
quality
purified
impurities
≤1.0% water
pH
5.0-7.5
solubility
soluble, clear, colorless
cation traces
Al: ≤5 mg/kg, As: ≤0.05 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤50 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤1000 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg
UV absorption
λ: 260 nm Amax: ≤0.3, λ: 280 nm Amax: ≤0..2
suitability
no residue for filter test
storage temp.
2-8°C
SMILES string
O2C(C2)C.O1CC1
InChI
1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2
InChI key
RVGRUAULSDPKGF-UHFFFAOYSA-N
General description
Application
- as an inhibitor of lipoprotein lipase activity to assess hepatic very-low-density lipoprotein (VLDL)- triglyceride (TG) secretion in mice
- for VLDL secretion assay in mice
- to intraperitoneally inject the mice by dissolving in phosphate buffer saline (PBS) for hepatic triglyceride production
Biochem/physiol Actions
1 of 1
This Item | |||
|---|---|---|---|
| suitability no residue for filter test | suitability - | suitability - | suitability - |
| form powder | form powder | form solid | form solid |
| storage temp. 2-8°C | storage temp. - | storage temp. 2-25°C | storage temp. - |
| impurities ≤1.0% water | impurities ≤0.25% ethylene glycol and diethylene glycol, ≤0.4% total ash, ≤0.75% water, ≤1 ppm ethylene oxide, ≤2 ppm arsenic traces, ≤20 ppm heavy metals, ≤5 ppm dioxan, ≤5 ppm propylene oxide, 50-125 ppm butylhydroxytoluene | impurities - | impurities - |
| solubility soluble, clear, colorless | solubility 10%, clear, colorless | solubility - | solubility - |
| Quality Level 100 | Quality Level 100 | Quality Level 500 | Quality Level 300 |
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Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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How can I determine the shelf life / expiration / retest date of this product?
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
Helpful?
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What does the number in poloxamer-407, 105, 108, etc. stand for?
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The numeric suffix in various forms of Poloxamers refers to the mass per mole of polyoxypropylene and the percentage of polyoxyethylene present in that specific compound.
Helpful?
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In poloxamer-407,105, 108 etc. This number stands for?
1 answer-
Poloxamers are block co-polymers that have a basic structure of one central polyoxypropylene core adjoined to two polyoxyethylene side blocks or chains. The numeric suffix designated in various forms of Poloxamers is in reference to the mass per mole of polyoxypropylene and the percentage of polyoxyethylene present within that specific compound.
See the link below for additional information. Examples can be found in Table 1 on page 2.https://nmr.oxinst.com/assets/uploads/MagRes/App%20Notes/X-Pulse/App_Note_3_Poloxamer_Oct_2019.pdf
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