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Merck

1368008

USP

3,3′,5-三碘代-L-甲状腺原氨酸

United States Pharmacopeia (USP) Reference Standard

别名:

O-(4-羟基-3-碘苯基)-3,5-二碘代-L-酪氨酸, T3, 碘噻罗宁

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About This Item

经验公式(希尔记法):
C15H12I3NO4
CAS号:
分子量:
650.97
Beilstein:
2710227
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

liothyronine

製造商/商標名

USP

mp

234-238 °C (lit.)

應用

pharmaceutical (small molecule)

格式

neat

儲存溫度

2-8°C

SMILES 字串

N[C@@H](Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)C(O)=O

InChI

1S/C15H12I3NO4/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22/h1-4,6,12,20H,5,19H2,(H,21,22)/t12-/m0/s1

InChI 密鑰

AUYYCJSJGJYCDS-LBPRGKRZSA-N

基因資訊

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一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Liothyronine USP reference standard for use in specified quality tests and assays.

Also used to prepare standard, standard stock, Liothyronine stock, and resolution solutions for assay, and identification test according to given below monographs of the United States Pharmacopeia (USP):
  • Thyroid
  • Levothyroxine Sodium Tablets
  • Liothyronine Sodium Tablets

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他說明

Sales restrictions may apply.

象形圖

Health hazard

訊號詞

Danger

危險聲明

危險分類

STOT RE 1

標靶器官

Thyroid,Cardio-vascular system,Kidney

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析证书(COA)

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访问文档库

Liothyronine Sodium Tablets
United States Pharmacopeia, 34(4), 2640-2640 (2013)
Levothyroxine Sodium Tabletsl
United States Pharmacopeia, 42(2), 2618-2618 (2022)
Thyroid
United States Pharmacopeia, 40(5), 4362-4362 (2023)
Sara Santos Bernardes et al.
Cell and tissue research, 357(3), 803-814 (2014-05-21)
The role of reactive oxygen species (ROS) in muscle protein hydrolysis and protein oxidation in thyrotoxicosis has not been explored. This study indicates that ROS play a role in skeletal muscle wasting pathways in thyrotoxicosis. Two experimental groups (rats) were
Akihiro Mouri et al.
Psychoneuroendocrinology, 48, 147-161 (2014-07-13)
Attention deficit/hyperactivity disorder (ADHD) has been reported in association with resistance to thyroid hormone, a disease caused by a mutation in the thyroid hormone receptor β (TRβ) gene. TRβ is a key protein mediating down-regulation of thyrotropin (TSH) expression by

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